erythrokeratoderma variabilis

erythrokeratoderma var·i·a·bi·lis

A hereditary skin disease characterized by tough, scaly plaques associated with erythroderma that may vary daily in size, shape, and position.
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6) Erythrokeratoderma variabilis is reported to worsen during pregnancy.
Chanarin-Dorfman syndrome mostly present as congenital ichthyosiform erythroderma but can also manifest as lamellar ichthyosis and erythrokeratoderma variabilis like picture.
Progressive symmetric erythrokeratoderma is clinically different from erythrokeratoderma variabilis (EKV) first described by Mendes da Costa) its closest differential diagnosis, by well- demarcated non-migratory erythematous plaques in contrast to the migratory plaques seen in the latter.