error-prone polymerase chain reaction (PCR)

er·ror-prone po·ly·mer·ase chain re·ac·tion (PCR)

(er'ŏr-prōn pol'im-ĕr-ās chān rē-ak'shŭn)

Use of PCR under conditions in which misincorporation of bases is favored, e.g., where random mutants are sought for a portion of amplified DNA.