equianalgesic dose


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e·qui·an·al·ge·sic dose

the qualitative ratio between actual milligram potency of comparable analgesics required to achieve the equivalent therapeutic effect.

equianalgesic dose

A dose of one form of analgesic drug equivalent in pain-relieving effect to another analgesic. In pain control, this equivalence permits substitution of one analgesic to avoid undesired side effects from another.
See also: dose

e·qui·an·al·ge·sic dose

(ēkwē-anăl-jēzik dōs)
Qualitative ratio between actual milligram potency of comparable analgesics required to achieve the equivalent therapeutic effect.
References in periodicals archive ?
When switching to methadone from another drug, the reduction in the equianalgesic dose should be greater, usually 75% to 90%.
Equianalgesic doses for conversion from one oral opioid to another *,([dagger]) Conversion to/from oral morphine equivalent--multiply by Equivalence to Opioid 30 mg morphine (mg) To From Morphine 30 1 1 Codeine 200 0.15 6.67 Oxycodone 20 1.5 0.67 Hydromorphone 6 5 0.2 Dihydrocodeine 180 0.16 6 Tramadol ~1:10 ([double dagger]) * Adapted from the Canadian National Opioid Use Guideline Group (2010).
"Our findings indicate that opioids increase the risk of fractures among older patients with arthritis, and suggest that clinicians should be alert to the possibility that short-acting opioids pose a significantly greater risk of fractures among older adults than do equianalgesic doses of long-acting opioids, especially during the first 2 weeks" of therapy, he said.
"We recently reported clinical studies demonstrating the superiority of MoxDuoIR in terms of tolerability compared to equianalgesic doses of morphine, oxycodone and Percocetcentsc for the management of acute post-operative pain.