Epostane, a 3[beta]-hydroxysteroid dehydrogenase inhibitor, prevents progesterone synthesis however requires dosing each 6 hrs for 7 days to result abortion.
Termination of early pregnancy by the 3[beta]--hydroxysteroid dehydrogenase inhibitor epostane.
Termination of Early Pregnancy by the 3 Beta Hydroxysteroid Dehydrogenase Inhibitor Epostane
," New England Journal of Medicine, 319:813, 1988.
Progesterone synthesis inhibitors such as epostane
could be effective, as they interfere at several levels in the establishment of pregnancy.