epostane

epostane

an antiprogesterone agent used to terminate pregnancy in dogs and to induce farrowing in sows.
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References in periodicals archive ?
Epostane, a 3[beta]-hydroxysteroid dehydrogenase inhibitor, prevents progesterone synthesis however requires dosing each 6 hrs for 7 days to result abortion.
Termination of early pregnancy by the 3[beta]--hydroxysteroid dehydrogenase inhibitor epostane.
Termination of Early Pregnancy by the 3 Beta Hydroxysteroid Dehydrogenase Inhibitor Epostane," New England Journal of Medicine, 319:813, 1988.
Progesterone synthesis inhibitors such as epostane could be effective, as they interfere at several levels in the establishment of pregnancy.