epithelioid leiomyoma


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leiomyoma

 [li″o-mi-o´mah]
a benign tumor derived from smooth muscle, most often of the uterus (leiomyoma uteri).
bizarre leiomyoma epithelioid leiomyoma.
leiomyoma cu´tis one arising from cutaneous or subcutaneous smooth muscle fibers, found singly or multiply, usually as lesions arising from arrectores pilorum muscles; it may also occur as a solitary genital lesion or a solitary angioleiomyoma arising from the muscle of veins.
epithelioid leiomyoma one in which the cells are polygonal rather than spindle shaped, usually found in the stomach. Called also bizarre leiomyoma and leiomyofibroma.
leiomyoma u´teri (uterine leiomyoma) leiomyoma of the uterus; called also uterine myoma and, colloquially, fibroids. It is the most common of all tumors found in women. It may occur in any part of the uterus, although it is most frequently in the body of the organ.

Leiomyomas usually occur during the third and fourth decades, and are often multiple, although a single tumor may occur. They are usually small but may grow quite large and occupy most of the uterine wall; after menopause, growth usually ceases. Symptoms vary according to the location and size of the tumors. As they grow they may cause pressure on neighboring organs, painful menstruation, profuse and irregular menstrual bleeding, vaginal discharge, or frequent urination, as well as enlargement of the uterus.

In pregnancy, the tumors may interfere with natural enlargement of the uterus with the growing fetus. They may also cause spontaneous abortion and death of the fetus.

Small leiomyomas are usually left undisturbed and are checked at frequent intervals. Larger tumors may be removed surgically, sometimes accompanied by a hysterectomy, or medication may be prescribed to induce a temporary menopause.
Leiomyoma of the uterus. The tumors may be subserosal, intramural, or submucosal. Subserosal and submucosal tumors may be pedunculated and may protrude from the uterine surface or into the uterine cavity, respectively. The stalk of pedunculated tumors may also become twisted. From Damjanov, 2000.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

epithelioid leiomyoma

A leiomyoma, usually of the stomach.
See also: leiomyoma
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Epithelioid leiomyoma of uterus is a rare variant of leiomyoma composed of round or polygonal 'clear' cells rather than typical spindle-shaped cells.
To best of our knowledge this is the first report related with unilateral ovarian agenesis together with epithelioid leiomyoma, clear cell type.
(4,5) Though Epithelioid cells, Spindle cells, Giant cells, Eosinophilic cells, Stromal Hyalinization are common features for both PEcomas and epithelioid leiomyoma, presence of network of capillaries are exclusively a feature PEComa.
Appelman and Helwig have postulated that gastric stromal tumor may originate from mesenchymal cells other than smooth muscle cells.[3-5] The spindle cell neoplasms of the gastrointestinal tract were called leiomyoma or leiomyosarcoma, and the predominant round or polygonal cell variant was named epithelioid leiomyoma, leiomyoblastoma, or epithelioid leiomyosarcoma.[3-9] Despite advanced immunohistochemical and ultrastructure studies, the line of differentiation (smooth muscle, neural, gastrointestinal, autonomic nerve, or undifferentiated) is still inconclusive.[10-15] As a result, the noncommittal term gastrointestinal stromal tumor has been adopted to describe this heterogeneous group of neoplasms.[16]
These include nonkeratinizing squamous carcinoma, cutaneous adnexal tumor,[2] carcinoid tumor, melanocytic neoplasms,[2] epithelioid leiomyoma, and hemangiopericytoma.[13] In general a panel of immunohistochemical stains should prove useful, when necessary, in excluding these diagnostic possibilities.