epithelioid hemangioendothelioma

epithelioid hemangioendothelioma

angiocentric vascular tumor with metastatic potential composed of epithelioid endothelial cells arranged in short cords or nests surrounded by myxohyaline stroma.
References in periodicals archive ?
Epithelioid hemangioma is a benign lesion and must be distinguished by the pathologist from epithelioid hemangioendothelioma and epithelioid angiosarcoma, which are low- and high-grade malignancies, respectively.
Functional hyposplenism due to a primary epithelioid hemangioendothelioma of the spleen.
Sanzone did not suffer from angiosarcoma, but from epithelioid hemangioendothelioma (EHE), a disease whose only known medical link is to birth control pills.
Epithelioid hemangioendothelioma of the bone is a rare vascular tumor of borderline malignancy.
Such a panel might include CD45, CD20, CD3, or CD30 for large cell lymphomas; S100 and HMB-45 for melanoma; and CD31 and CD34 for angiosarcoma and epithelioid hemangioendothelioma.
ALHE is believed to be neoplastic in origin and to represent a benign form of a spectrum of vascular proliferations, including epithelioid hemangioendothelioma and epithelioid angiosarcoma.
In the differential diagnosis of the splenic tumor, primary splenic epithelioid hemangioendothelioma may be a consideration, as this neoplasm can exhibit short cords of plump epithelioid and spindle cells in abundant hyaline matrix similar to the pattern seen in our case.
1) Spindle-cell hemangioendothelioma and epithelioid hemangioendothelioma share many features, but the latter exhibits a more solid growth pattern and an absence of cavernous spaces, thrombi, phleboliths, and discrete spindle-cell areas.
22,23) Desmoplastic small round cell tumor and synovial sarcoma may express calretinin, (24,25) and epithelioid angiosarcoma and epithelioid hemangioendothelioma are positive for D2-40 and podoplanin.
5) Other vascular lesions, such as epithelioid hemangioendothelioma, spindle cell hemangioendothelioma, and intravascular papillary endothelial hyperplasia, are excluded in a similar fashion.
2,13) Epithelioid hemangioendothelioma occurs more commonly in soft tissue and bones than in lymph nodes.
Epithelioid hemangioendothelioma may show focal high-grade areas, with cellular atypia and a sheeted architecture, but most cells reside in small nests and trabeculae.