We have shown that CAR acts downstream of TNF - induced signalling to promote trans - epithelial migration
of immune cells both in vitro and in vivo.
Proenca et al., "Nerve growth factor promotes corneal epithelial migration
by enhancing expression of matrix metalloprotease-9," Investigative Ophthalmology & Visual Science, vol.
Trefoil peptides promote epithelial migration
through a transforming growth factor beta-independent pathway.
Both contain growth factors such as substance P, insulin-like growth factor-1, and nerve growth factor for promoting corneal epithelial migration
Same as the vascular distribution, the direction of epithelial migration
is outward from the manubrium of malleus to annulus .
Strain forces exerted in the ECM in vitro have been shown to induce fibronectin-mediated epithelial cell migration by activating the extracellular signal-regulated kinase (ERK) and myosin light chain (MLC) signalling pathways, indicating the importance of fibronectin in wound closure and epithelial migration
However, the specific mechanisms of how SC-MN directs epithelial migration
and proliferation downstream of MR are unknown.
The plasma proteins act as a scaffold for the bone, connective tissue and epithelial migration
. The placement of a supra-physiologic concentration of autologous platelets (PRP) was found to be useful in enhancing the wound healing in chronic leg ulcers without any adverse events.
Some studies have reported that a sharp posterior optic edge is the main factor in preventing PCO (KOHNEN et al., 2008) due to the "barrier effect" against lens epithelial migration
(APPLE et al., 2001).
VEGF is a cytokine that promotes angiogenesis and MIP-3[alpha] functions in epithelial migration
and mucosal barrier repair.
Topical diclofenac inhibits corneal epithelial migration
at high doses but not at clinical doses; moreover, it can induce expression of matrix metalloproteinases in corneal tissue.
(1) They are believed to form as the result of poor eustachian tube function with resultant tympanic membrane retraction and a lack of normal epithelial migration
. Cholesteatomas are thought to erode bony structures through a combination of enzymatic activity and pressure necrosis.