epimer

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Related to epimers: Mutarotation, Anomers

epimer

 [ep″ĭ-mer]
one of two or more optical isomers that differ only in the configuration around one asymmetric carbon atom. adj., adj epimer´ic.

ep·i·mer

(ep'i-mĕr),
One of two molecules (having more than one chiral center) differing only in the spatial arrangement about a single chiral atom, for example, α-d-glucose and α-d-galactose (with respect to carbon-4).
See also: sugars. Compare: anomer.
[epi- + G. meros, part]

ep·i·mer

(ep'i-mĕr)
One of two molecules (having more than one chiral center) differing only in the spatial arrangement about a single chiral atom.
See: sugars
Compare: anomer
[epi- + G. meros, part]
References in periodicals archive ?
Two C-24 epimers, (20R,24R)-3,6-diacetyl-epoxydammar-3[beta],6[alpha],12[beta],25-t etraol (3) and (20R,24S)-3,6-diacetyl-epoxydammar-3[beta],6[alpha],12[beta],25-t etraol (4), were synthesized and their structures were identified by HR-MS, 1H NMR, 13C NMR and X-ray single-crystal diffraction.
It was found that 3[alpha]-[[sup.18]F]FCA shows slightly faster hepatobiliary transport than its epimer, 3[beta]-[[sup.18]F]FCA.
Caption: Figure 2: Comparison of the separation of budesonide epimers with four different columns during method development.
The authors obtained good signal resolutions (Rs > 1) and average recoveries (79-95%) even when epimers are included and demonstrated that other antibiotics and conventional feed ingredients do not interfere with the analysis conveying high specificity.
In the present study, a rapid, sensitive, and specific LCMS was developed and validated for stereoselective determination and pharmacokinetic studies of 20(R)- and 20(S)ginsenoside Rh1 and 20(R)- and 20(S)-ginsenoside Rg3 epimers in rat plasma after oral administration of Radix Ginseng Rubra or SMS extracts.
The isolated compounds were identified in each chromatogram whenever possible, whereas compounds 1a/b and 2 gave one sharp peak at 22.4 min, compound 3, a peak at 26.7 min, and the two epimers 4 and 5 appeared as one sharp peak at 28.5 min (Fig.
Misleading measures in vitamin D analysis: a novel LCMS/ MS assay to account for epimers and isobars.
Meanwhile, lectins have unique ability to distinguish subtle structural differences among saccharides, e.g., epimers, anomers, and linkage isomers, etc.
No attempt was made to distinguish between sterol epimers at [C.sub.24].
baumannii may also have equal specificity for glucose as well as mannose, because mannose and glucose are epimers at C-2.
Pheophorbide a and two related epimers were drawn in ChemSketch [33] based on reported structure by Lai et al.