epimer


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epimer

 [ep″ĭ-mer]
one of two or more optical isomers that differ only in the configuration around one asymmetric carbon atom. adj., adj epimer´ic.

ep·i·mer

(ep'i-mĕr),
One of two molecules (having more than one chiral center) differing only in the spatial arrangement about a single chiral atom, for example, α-d-glucose and α-d-galactose (with respect to carbon-4).
See also: sugars. Compare: anomer.
[epi- + G. meros, part]

epimer

/ep·i·mer/ (ep´ĭ-mer) either of two optical isomers that differ in the configuration around one asymmetric carbon atom.

ep·i·mer

(ep'i-mĕr)
One of two molecules (having more than one chiral center) differing only in the spatial arrangement about a single chiral atom.
See: sugars
Compare: anomer
[epi- + G. meros, part]

epimer

one of two or more isomers which differ only in the configuration about one carbon atom.
References in periodicals archive ?
51 in compounds 4 and 5, respectively, denoting that 5 is the 25S epimer of 4 (25R) (Agrawal 2005) (Table 1).
As seen with 25(OH)D, epimerization can lead to high concentrations of the C-3 epimer, 3-epi1,25[(OH).
25-0H Vitamin D is a challenging analyte to accurately measure in human blood due to the presence of 25-0H Vitamin D2, Vitamin D binding proteins, 25-0H Vitamin D metabolites such as 24, 25 (OH)2 Vitamin D, and C-3 epimers of 25-0H Vitamin D.
In addition, we will be separating and quantifying the C3 epimer of 25-[OHD.
8) showed that commonly used LC-MS/MS procedures may overestimate the 25(OH)D concentration when the C-3 epimer accounts for a substantial proportion of the circulating 25(OH)[D.
In the chimeric mouse urine only the epimer of VII (VIIc) could not be detected under the current instrumental conditions, but it should be noted that in humans VIIc is only a minor metabolite.
Schmidt's comments give the false impression that our recently published HPLC method (1) is unable to identify the presence of the C-3 epimer apart from 25(OH)[D.
Without chromatographic resolution of the 2 compounds, the epimer could mistakenly be reported as 25(OH)[D.
7-Hydroxydehydroepiandrosterone epimers in human serum and saliva.
ESR study on the structure-antioxidant activity relationship of tea catechins and their epimers.
While individually quantitating D2 and D3 isomers, the Topaz System running the Vitamin D 200M Assay Kit, also automatically differentiates between D3 epimers, providing the specificity to deliver highly accurate diagnostic results in a single analysis.
The retention times for the two epimers on all four columns were found to be similar, and were unaffected by the pH of the eluent.