Komossa et al (25) found that risperidone is less epileptogenic
than clozapine, with a relative risk of .(22).
Fast oscillations on the scalp have been identified in several studies [36, 38, 39], and the suitability of surface-recorded fast oscillations to demarcate seizure-generating tissue and to indicate its epileptogenic
potential seems meanwhile undoubted [5, 39].
But interestingly, three cases in the ADHD group showed abnormal focal epileptogenic
activity in the frontal lobe in their EEGs despite negative previous history of seizures.
Li et al., "Dynamic network connectivity analysis to identify epileptogenic
zones based on stereo-electroencephalography," Frontiers in Computational Neuroscience, vol.
Potential biomarker of epileptogenic
zone includes high-frequency oscillations.
The patient was monitored closely for convulsive and/or nonconvulsive seizures during the time of her admission by three-day video EEG monitoring, and three spot EEGs, all within 10 days of the CT perfusion, and none of them demonstrated the transformation of the epileptogenic
discharges into seizures.
Moreover, in TLE, hyper-excitability in the hippocampus is also seen during the process of epilepsy development and can contribute to an epileptogenic
focus by inducing atrophy of the hippocampus (see review [45-49]).
During the UHW operation, Professor William Gray used the neuromate's robotic arm and spent 55 minutes identifying and operating on the "epileptogenic
zone" in a procedure that would normally take four hours.
No correlation was found between the laterality of the epileptogenic
focus in the epilepsy group and existence of IHI, nor between age and HIA values among the groups.
So that, the first description of the technique hemispherectomy based in removal of epileptogenic
hemisphere (anatomical hemispherectomy) evolved to many techniques of functional hemispherectomy, whose it is based in the disconnection between the epileptogenic
hemisphere and contralateral hemisphere and deep brain structures without creating a cavit (1,2,3,24,21,23,48,54,55,57,58,61).
network in MTLE also varies between individuals.
It is therefore possible that some developmental or childhood brain injury has occurred in a person with ApoE [epsilon]4, and there may be a failure to repair the damage, resulting in an epileptogenic