epigallocatechin gallate, EGCG

epigallocatechin gallate, EGCG

An antioxidant substance found in green tea that is claimed to be protective against a range of common cancers. EGCG markedly reduces phosphorylation of the receptor for VASCULAR ENDOTHELIAL GROWTH FACTOR, thus disrupting the autocrine pathway that protects the cell from APOPTOSIS.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005