According to this mechanism, conditions that increase abdominal pressure, such as obesity or pregnancy, compress the dural sac, reduce the dual surface area, and reduce the epidural cavity
volume so that the final level of the drug injected is higher when the drug is injected into the epidural space [27, 28].
Immunohistochemical studies have indicated that the immune system perceives the nuclear material in the epidural cavity as a foreign matter and tries to wipe it out.
Following the routine anesthetic evaluation of our patients, epidural cavity was reached with use of spinal needle by finding the appropriate level under the control of scopy and supervision of anesthetist with slight sedation in operating room conditions.
Autologous blood injection to the spinal epidural cavity
[epidural blood patch (EBP)] is one of the most effective therapy methods in cases that conservative approaches are unsuccessful (2).