epidermolysis


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epidermolysis

 [ep″ĭ-der-mol´ĭ-sis]
a loosened state of the epidermis with formation of blebs and bullae either spontaneously or at the site of trauma.
epidermolysis bullo´sa a variety with development of bullae and vesicles, often at the site of trauma; in the hereditary forms, there may be severe scarring after healing, or extensive denuded areas after rupture of the lesions.

ep·i·der·mol·y·sis

(ep'i-dĕr-mol'i-sis), Avoid the mispronunciation epidermoly'sis.
A condition in which the epidermis is loosely attached to the corium, readily exfoliating or forming blisters.
[epidermis + G. lysis, loosening]

epidermolysis

/epi·der·mol·y·sis/ (-der-mol´ĭ-sis) a loosened state of the epidermis with formation of blebs and bullae, occurring either spontaneously or at the site of trauma.epidermolyt´ic
epidermolysis bullo´sa  a variety with development of bullae and vesicles, often at the site of trauma; in the hereditary forms, there may be severe scarring after healing, or extensive denuded areas after rupture of the lesions.

epidermolysis

Dermatology The shearing of the epidermis from the dermis, generally with an accumulation of fluid and formation of blebs and bullae. See Epidermolysis bullosa.

ep·i·der·mol·y·sis

(ep'i-dĕr-mol'i-sis)
A condition in which the epidermis is loosely attached to the corium, readily exfoliating or forming blisters.
[epidermis + G. lysis, loosening]

epidermolysis

Separation of the outer layer of the skin from the underlying CORIUM, usually with the formation of a blister. Epidermolysis is a feature of many skin disorders.

ep·i·der·mol·y·sis

(ep'i-dĕr-mol'i-sis) Avoid the mispronunciation epidermoly'sis.
A condition in which the epidermis is loosely attached to the corium, readily exfoliating or forming blisters.
[epidermis + G. lysis, loosening]

epidermolysis

a loosened state of the epidermis with formation of blebs and bullae either spontaneously or at the site of trauma.

epidermolysis bullosa
a hereditary disease of humans, Collie dogs, Shetland sheepdogs, Suffolk, South Dorset Down and Scottish blackface sheep, and Simmental and Brangus calves. Characterized by epidermal bullae, particularly on areas of pressure or trauma and in sheep in the mouth and on woolless skin. There may be shedding of hooves and horns. Called also red foot disease.
congenital bovine epidermolysis
ulcers on lips, gums, tongue, muzzle and limb extremities at birth; skin lesions may be local alopecia without ulceration; resembles epidermolysus bullosa simplex in humans; an autosomal dominant recorded in Simmentals.
References in periodicals archive ?
Its product development pipeline includes two drug candidates for treating epidermolysis bullosa, gout, type II diabetes, hemophilic arthropathy, and immunodermatology diseases.
The researchers described the case of a 7-year-old boy who was admitted to a children's hospital in Germany in June 2015 with junctional epidermolysis bullosa so severe that approximately 80% of his total body surface area was affected.
James has been campaigning to help the national charity DEBRA (the Dystrophic Epidermolysis Bullosa Research Association) raise awareness and money, in the hope that a cure can be found.
7 The aim of presenting these two case reports was to describe the oral and dental features of two different types of Epidermolysis bullosa; simplex and dystrophic types and to discuss their dental management.
Abeona is also developing EB-101 (gene-corrected skin grafts) for recessive dystrophic epidermolysis bullosa (RDEB), ABO-201 (AAV-CLN3) gene therapy for juvenile Batten disease (JBD); and ABO-301 (AAV-FANCC) for Fanconi anemia (FA) disorder using a novel CRISPR/Cas9-based gene editing approach to gene therapy for rare blood diseases.
The report provides a snapshot of the global therapeutic landscape of Epidermolysis Bullosa
Revised classification system for inherited epidermolysis bullosa: Report of the Second International Consensus Meeting on diagnosis and classification of epidermolysis bullosa.
The report reviews key players involved in the therapeutics development for Epidermolysis Bullosa and enlists all their major and minor projects
Epidermolysis bullosa, a condition involving mostly the skin, can also be associated with severe mucosal injury that may cause serious medical complications more threatening to the patient's outcome than surface ones.
Anaesthesia for children with epidermolysis bullosa: A review of 20 years' experience.
Progress in epidermolysis bullosa: from eponyms to molecular genetics classification.
This report provides information on the therapeutic development for Epidermolysis Bullosa, complete with latest updates, and special features on late-stage and discontinued projects.

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