Di Stefano et al., "MicroRNA-210 modulates endothelial cell response to hypoxia and inhibits the receptor tyrosine kinase ligand ephrin-A3," The Journal of Biological Chemistry, vol.
Wu, "Dissecting the roles of ephrin-A3 in malignant peripheral nerve sheath tumor by TALENs," Oncology Reports, vol.
Binding of glial ephrin-A3 to neuronal EphA4 maintains normal spine morphology  while preventing the interaction results in unstable spines with disrupted shapes .
Interfering with EphA4 or ephrin-A3 induces growth of astrocytic processes in cell culture .
Ephrin-A3 and -B3 were preferentially expressed in the brain, whereas ephrin-A2 and -A4 expression was highest in the colon.
Ephrin-A3 mRNA expression was up-regulated 26-fold in squamous cell lung carcinoma.
The interaction between ephrin-A3 and EphA4, which are expressed by astrocytes and dendritic spines of neurons, respectively, is involved in decreasing levels of GLAST and glutamate transporter 1 (GLT-1) for proper synapsing to occur [115-118].
Pasqualea, "Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport," Proceedings of the National Academy of Sciences of the United States of America, vol.