The cytokines detected were IFNI3, IL-10, IL-12p70, IL-13, IL-2, IL-5, IP-10, MiP-1[alpha], MiP-1[beta], IL-6, IL1-RA, GM-CSF, RANTES, IL-1[beta], Eotaxin
, Basic FGF, VEGF, PDGF-[beta], MCP-1, IL-8, IL15, IL-17, G-CSF, IL-12p70, IL17A, IL-9 and TNF-[alpha].
The 27 cytokines and chemokines investigated were IL-1[beta], IL-1r, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12p70, IL-13, IL-15, IL-17a, Eotaxin
, basic PDGF, G-CSF, GM-CSF, IFN-[gamma], IP-10, MCP-1(MCAF), MIP-1[alpha], MIP-1[beta], PDGF-BB, RANTES, TNF- [alpha] and VEGF.
Studies with advanced cancer patients have shown reductions in C-reactive protein; interleukins la, 2, and 8; tumor necrosis factor a; and eotaxin
with IV C therapy.
The material is derived from green citrus unshiu, which contains synephrine and hesperidin, which are said to regulate eotaxin
synthesis, and naringin, which decreases histamine release.
levels in patients with chronic spontaneous urticaria.
They display increased responsiveness, adhesiveness, migration, and degranulation [10, 11] and are characterized by upregulated secretion of their mediators, for example, eosinophilic cationic protein  or eotaxin
The concentrations of the following circulation cytokines and chemokines were measured: IL-1[alpha], IL-1[beta], IL-1ra, IL-2, sIL-2R[alpha], IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12(p40), IL-12(p70), IL-13, IL-15, IL-17a, sCD40L, EGF, Eotaxin
, FGF2, Flt-3 ligand, Fractalkine, G-CSF, GM-CSF, GRO, IFNa2, IFN-[gamma], IP-10, MCP-1, MCP-3/CCL7, MDC/CCL22, MIP-1a, MIP-1[beta], TGF[alpha], TNF[alpha], TNF[beta], and VEGF.
Imai et al., "Molecular cloning of human eotaxin
, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin
receptor, CC chemokine receptor 3," The Journal of Biological Chemistry, vol.
Mao et al., "High plasma levels of MCP-1 and eotaxin
provide evidence for an immunological basis of fibromyalgia," Experimental Biology and Medicine, vol.
This assay kit measured protein concentrations of chemokines: eotaxin
, fractalkine, interferon-gamma inducible protein-10 (IP-10), monocyte inflammatory protein (MCP)-1, macrophage inhibitory protein (MIP)-1a, and RANTES; proinflammatory cytokines: granulocyte macrophage colony-stimulating factor (GMCSF), interleukin--(IL-) 1[beta], IL-2, IL-12(p40/p70), IL-6, IL7, IL-8, IL-15, IL-17, tissue necrosis factor--(TNF-) [alpha], and interferon- (IFN-)[gamma]; anti-inflammatory cytokines: IL-1RA, IL-4, IL-5, IL-10, IL-13, and IFN-a; and growth factors: vascular endothelial growth factor (VEGF), melanoma growth stimulatory activity (GRO), epidermal growth factor (EGF), fibroblast growth factor (FGF)-2, and platelet-derived growth factor (PDGF-AA and PDGF-BB).
Finally, in another ocular fluid, the aqueous humour; higher levels of proteins involved in AD pathology such as [beta]-amyloid peptides; and a series of chemokines, including eotaxin
3, and interleukin [IL]-8 (160) were detected in cataract surgery patients.
Biochemical Wilks's Partial F P Tolerance 1-toler marker lambda Wilks's 5 BDNF 0.636 0.891 5.733 0.021 0.851 0.148 BLC 0.601 0.943 2.840 0.099 0.796 0.204 Eotaxin
0.589 0.963 1.818 0.184 0.582 0.418 Eotaxin-2 0.581 0.976 1.143 0.290 0.678 0.322 E-Selectin 0.571 0.993 0.332 0.567 0.393 0.607 ICAM-1 0.577 0.983 0.815 0.371 0.661 0.339 IGFBP-1 0.623 0.911 4.603 0.037 0.724 0.276 IGFBP-2 0.567 0.100 0.001 0.995 0.512 0.487 L-Selectin 0.603 0.941 2.961 0.092 0.397 0.602 MIP-1d 0.567 0.100 0.004 0.951 0.691 0.309 MIP-3b 0.567 0.100 0.002 0.966 0.836 0.164 PECAM-1 0.657 0.863 7.453 0.009 0.779 0.221 VCAM-1 0.571 0.993 0.336 0.565 0.634 0.366 Table 4: Predictive value of selected markers marked with discriminant analysis by stepwise forward selection method.