eosinophilic meningoencephalitis

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e·o·sin·o·phil·ic me·nin·go·en·ceph·a·li·tis

a disease most commonly caused by infection by the rat lungworm, Angiostrongylus cantonensis, the larvae of which, ingested with infected slugs or land snails (or some unidentified transport host), migrate from intestine to the meninges of the brain where the disease is produced; it is usually mild, of short duration, and characterized by fever, eosinophilia, and white blood cells (rarely nematode larvae) in the spinal fluid. Manifestations are both meningeal and indicative of brain disfuction.


staining readily with eosin; pertaining to eosinophils or to eosinophilia.

cartilaginous eosinophilic streaks
streaks of eosinophilic matrix in cartilage. Some are normal zones of development, others represent areas of matrix degeneration and osteochondrosis.
eosinophilic chemotactic factor
a primary mediator of type I anaphylactic hypersensitivity, it is an acidic peptide (molecular weight 500) released by mast cells, which attracts eosinophils to areas where it is present.
equine eosinophilic chronic dermatitis
acanthosis and hyperkeratosis accompanied by eosinophilic granulomas in pancreas and other epithelial organs.
feline eosinophilic granuloma complex
a collective name given to the lesions of eosinophilic ulcer, eosinophilic plaque (below), and linear granuloma because of similarities in histopathology, clinical course and occasionally simultaneous occurrence in the cat.
eosinophilic granuloma
nodules or plaques that occur on skin or oral mucosa of dogs. Usually not pruritic, but oral lesions can cause some difficulties in eating. The cause is unknown. See also feline eosinophilic granuloma complex (above), equine nodular collagenolytic granuloma.
eosinophilic intestinal granuloma
see angiostrongyluscostaricensis.
eosinophilic lung disease
eosinophilic meningitis
see gnathostomaspinigerum.
eosinophilic meningoencephalitis
see sodium chloride poisoning, angiostrongyluscantonensis.
eosinophilic myocarditis
in cattle may be observed in normal animals at slaughter. Histologically there is a predominant eosinophil invasion of the heart muscle. May be accompanied by similar lesions in skeletal muscles.
eosinophilic plaque
well-defined, raised, ulcerated and extremely pruritic lesions that occur on the skin of cats, usually on the abdomen or hindlegs. There are large numbers of eosinophils present in the dermis and sometimes peripheral blood. See also eosinophilic granuloma (above), feline eosinophilic granuloma complex (above).
eosinophilic pneumonia
eosinophilic ulcer
a well-defined ulceration, usually on the upper lip of cats overlying the canine tooth, which is shallow initially but can become extremely erosive and sometimes neoplastic. Mildly irritating to the cat. Called also indolent ulcer, rodent ulcer. See also feline eosinophilic granuloma complex (above).
Enlarge picture
Bilateral eosinophilic ulcer. By permission from Kummel BA, Color Atlas of Small Animal Dermatology, Mosby, 1989


encephalomeningitis; inflammation of the brain and its meninges. Most meningoencephalitides in animals are bacterial and combine the fever, pain and rigidity of a meningitis with the tremor, convulsions and paralysis of an encephalitis. Localizing signs such as circling, falling to one side, unilateral facial paralysis and Jacksonian type seizures are more common than in a viral encephalitis.

bovine infectious meningoencephalitis
eosinophilic meningoencephalitis
see sodium chloride poisoning (in pigs).
listerial meningoencephalitis
pasteurella meningoencephalitis
can be caused by Pasteurella multocida or Mannheimiahaemolytica in calves and in horses, mules and donkeys. Clinical signs include tremor, opisthotonos, rotation of the eyeballs, blindness, collapse and coma.
Pug meningoencephalitis
an acute or chronic neurologic disease of young or adult Pugs with predominantly cerebral signs which include depression, circling, head pressing and blindness. Cerebellar signs sometimes also occur. A viral etiology is suspected.
streptococcal meningoencephalitis
a common complication of streptococcal septicemia of newborn pigs. The cause is usually Streptococcus suis type 1. The syndrome includes stiffness, tremor, blindness, recumbency and violent, paddling convulsions.
thromboembolic meningoencephalitis
West Nile equine meningoencephalitis
References in periodicals archive ?
In Brazil, the first 3 documented cases of eosinophilic meningoencephalitis occurred in 2007 in 2 cities in the southeastern state of Espirito Santo (3).
Clinical manifestations and outcome of patients with severe eosinophilic meningoencephalitis presumably caused by Angiostrongylus cantonensis.
Eosinophilic meningoencephalitis due to Angiostrongylus cantonensis as the cause of death in captive nonhuman primates.
Earlier case reports of diffuse unilateral subacute neuroretinitis or eosinophilic meningoencephalitis are compatible with Baylisascaris infection (4).

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