eosinophilic gastroenteritis

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Related to eosinophilic gastritis: eosinophilic gastroenteropathy

gastroenteritis

 [gas″tro-en″tĕ-ri´tis]
inflammation of the lining of the stomach and intestine. Psychologic causes may include fear, anger, and other forms of emotional upset. Allergic reactions to certain foods can cause the condition, as can irritation by excessive use of alcohol. Severe gastroenteritis, with such symptoms as headache, nausea, vomiting, weakness, diarrhea, and gas pains, may result from various infectious and contagious diseases, such as typhoid fever, influenza, and food poisoning.
eosinophilic gastroenteritis a disorder, commonly associated with intolerance to specific foods, marked by infiltration of the mucosa of the small intestine and frequently the stomach by eosinophils, with edema but without vasculitis and by eosinophilia of the peripheral blood. Symptoms depend on the site and extent of the disorder.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

e·o·sin·o·phil·ic gas·tro·en·ter·i·tis

disorder comprising abdominal pain, malabsorption, often obstructive symptoms, associated with peripheral eosinophilia and areas of eosinophilic infiltration of the stomach, small intestine, and colon. May have an allergic etiology and responds to elimination diet in some patients; corticosteroid therapy is also effective.
Farlex Partner Medical Dictionary © Farlex 2012

eosinophilic gastroenteritis

A rare (about 300 cases reported in the world literature) heterogeneous condition characterised by abundant eosinophils in the lamina propria, especially of the stomach and less commonly of the small and large intestine.

Aetiology
Idiopathic or associated with allergies (e.g., asthma, atopic eczema, food allergy—usually to milk or soy protein), connective tissue disease (e.g., scleroderma, polymyositis, and dermatomyositis), Crohn’s disease, and parasites (e.g., anisakiasis).

Clinical findings
Nausea, vomiting, diarrhoea, weight loss, abdominal pain (linked to ingestion of specific foods), fever, rebound tenderness, mesenteritis.

Lab
Often with increased eosinophils in peripheral blood.
 
Pathology
Eosinophils in mucosa, fibrosis of muscularis propria with thickening and rigidity with outlet obstruction.

Management
May respond to elimination diet; up to 90% respond to corticosteroids.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

e·o·sin·o·phil·ic gas·tro·en·ter·i·tis

Disorder comprising abdominal pain, malabsorption, often obstructive symptoms, associated with peripheral eosinophilia and areas of eosinophilic infiltration of the stomach, small intestine, and colon.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Chehade, "Eosinophilic gastritis in children: clinicopathological correlation, disease course, and response to therapy," American Journal of Gastroenterology, vol.
'Eosinophilic gastritis, eosinophilic gastroenteritis, and eosinophilic esophagitis are severe debilitating diseases with no approved therapies.
Allakos (ALLK), up 94% after reporting results from its placebo-controlled trial of AK002 in patients with eosinophilic gastritis and/or eosinophilic gastroenteritis.
* Allakos Inc (NASDAQ: ALLK): Phase 2 top-line data for AK002 in eosinophilic gastritis.

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