Eosinophil cationic protein levels in the supernatant of sputum were measured by UniCAP fluoroenzyme immunoassay (Pharmacia Upjohn AB, Uppsala, Sweden), with a detection limit 0.
Eosinophil cationic protein, produced by eosinophils' large secondary granules, has been developed as a marker for eosinophilic disease.
Human muscle protein degradation in vitro by eosinophil cationic protein (ECP).
Eosinophil cationic protein stimulates migration of human lung fibroblasts in vitro.
Eosinophil cationic protein has an RNase activity <1% of that shown by eosinophil-derived neurotoxin (15).
Structure and chromosome localization of the human eosinophil-derived neurotoxin and eosinophil cationic protein genes: evidence for intronless coding sequences in the ribonuclease gene superfamily.
Ribonuclease activity associated with human eosinophil-derived neurotoxin and eosinophil cationic protein
The eosinophil cationic protein
enhances the inflammatory reaction and damages the detrusor muscle, leading to fibrosis.
Objective: The study was carried out to evaluate the role of serum eosinophil cationic protein
(ECP) as a biological marker for the diagnosis and to assess the severity of bronchial asthma.
One explanation for the development of Raynaud's phenomenon and digital gangrene, in association with hypereosinophilia, is that major basic protein and eosinophil cationic proteins
located within the eosinophil granule matrix contributed to the formation of microthrombi.