enzyme inhibitor


Also found in: Dictionary, Encyclopedia, Wikipedia.

enzyme inhibitor

a molecule that prevents an enzyme from catalysing a reaction. Such inhibitors can compete with the normal substrate (see COMPETITIVE INHIBITION or can block the active site, preventing entry of the substrate (see NONCOMPETITIVE INHIBITION). Inhibition may be reversible or irreversible. Enzyme inhibitors often form part of a FEEDBACK MECHANISM to regulate a biochemical pathway.
References in periodicals archive ?
"Associations were evident after five years of use and increased with longer durations of use, particularly in patients who used angiotensin converting enzyme inhibitors for more than 10 years."
Agostoni, "Angioedema associated with angiotensin-converting enzyme inhibitor use: outcome after switching to a different treatment," Archives of Internal Medicine, vol.
Angioedema is a well-known side effect of angiotensin converting enzyme inhibitors (ACEi).
Angiotensin converting enzyme inhibitor induced angio-oedema: a review of the pathophysiology and risk factors.
Angiotensin I-converting enzyme inhibitor activity in fermented egg albumen
Dipeptidyl peptidase IV in angiotensin-converting enzyme inhibitor associated angioedema.
The cream is an enzyme inhibitor and works by blocking an enzyme necessary for hair to grow.
The researchers also found an enzyme inhibitor oxamate, which is known to reduce LDHA activity, operated in the same manner.
The researchers also found an enzyme inhibitor, oxamate - known to reduce LDHA activity - operated in the same manner: It also disrupted the metabolic system of pancreatic cancer cells.
The researchers also found an enzyme inhibitor, oxamate, which is known to reduce LDHA activity, operated in the same manner: It also disrupted the pancreatic cancer cells metabolic system.
Researchers also found that an enzyme inhibitor, oxamate, which is known to reduce LDHA activity, also disrupted the pancreatic cancer cells metabolic system.
SAN DIEGO - Angiotensin-con-verting enzyme inhibitor therapy may reduce the risk of age-related bone loss in elderly men.