enzyme immunoassay


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Related to enzyme immunoassay: ELISA, EIA, radioimmunoassay

en·zyme im·mu·no·as·say

any of several immunoassay methods that use an enzyme covalently linked to an antigen or antibody as a label; the most common types are enzyme-linked immunosorbent assay (ELISA) and enzyme-multiplied immunoassay technique (EMIT).
See also: enzyme-linked immunosorbent assay, enzyme-multiplied immunoassay technique.
Farlex Partner Medical Dictionary © Farlex 2012

en·zyme im·mu·no·as·say

(EIA) (en'zīm im'yū-nō-as'ā)
Procedure measuring antibodies to detect the analyte of interest and an enzyme linked to the antigen-antibody complex. The enzyme reacts with a substrate to produce a product that is measured to quantitate the amount of antigen-antibody formed.
See also: enzyme-linked immunosorbent assay, enzyme-multiplied immunoassay technique
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

enzyme immunoassay

Abbreviation: EIA
A rapid enzyme immunochemical method for determining the presence of an antigen, antibody, or hapten in the blood. In EIA an antigen or antibody is bound to an enzyme, e.g., horseradish peroxidase or alkaline phosphatase. The resulting molecule can bind specific immunological targets in body fluid samples and highlight their presence enzymatically. EIA, formerly known as enzyme-linked immunosorbent assay (ELISA), is used as one of the primary diagnostic tests for many infectious diseases, including treponema pallidum (the spirochete that causes syphilis) and HIV.
See also: immunoassay
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
We therefore established an enzyme immunoassay of urinary MVA, using a specific antibody (9).
Simplified high-performance liquid chromatography-mass spectrometry assay for measurement of tacrolimus and its metabolites and cross-validation with microparticle enzyme immunoassay. Ther Drug Monit 1995;17:504-10.
Under the company's clinical performance studies, the testing with the SEFRIA Fentanyl Urine Enzyme Immunoassay compared favorably to liquid chromatography-mass spectrometry (LC-MS) analysis in both sensitivity (identification of positive results) and specificity (identification of negative results).
Some of the key market players of the European enzyme immunoassay (EIA) market include Hoffmann-La Roche Ltd (Switzerland), Abbott (U.S.), bioMerieux SA (France), Siemens Healthcare GmbH (Germany), Alere (U.S.), BD (U.S.), Bio-Rad Laboratories, Inc.
Drs Rehle, Shisana, Parker and Puren reply: Westreich and colleagues express concerns about the applicability of the BED capture enzyme immunoassay to the South African epidemic with HIV subtype C as the predominant HIV clade.
Sanko Junyaku currently manufactures and markets two test kits for interstitial pneumonia, EITEST KL-6 (sandwich enzyme immunoassay method) and PICOLUMI KL-6 (electrochemiluminescence immunoassay) for measurement of KL-6, a serum marker that is highly distinctive for the diagnosis of the disease, under a sales agreement with Eisai.
Both the rapid test and enzyme immunoassay identified 34 women who were infected with HIV (for a prevalence of seven per 1,000); neither test yielded any false-negative results.
Combining Shiga toxin enzyme immunoassay with Sorbitol-MacConkey agar screening optimizes the detection of Escherichia coli, reported Dr.
CHICAGO -- A rotavirus enzyme immunoassay should be the initial screen -- prior to stool cultures--in all children under 6 years of age with diarrheal illness during rotavirus season, Dr.
Louis, MO 3/21/02--Sigma-Aldrich announced that it has signed a non-biding letter of intent to sell its enzyme immunoassay (EIA) product line to IVAX Diagnostics.
Repeat HIV serologic testing showed a positive HIV enzyme immunoassay and a positive Western blot with bands at gp120, gp160, and p24.