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In many cases, the decision to administer adjunctive chemotherapy rests on certain histopathologic risk factors detected during the pathologic examination of enucleated eyes.
One real benefit of these systems, particularly of the organotypic in vitro preparations, is that the manifestation of toxicity can be extrapolated immediately to the manifestation in vivo; for example, corneal damage in the enucleated eye corresponds directly to potential corneal damage in vivo (although it must be recognized that these assays do not address the key parameter of recovery), or a neural tube defect in whole-embryo culture is expected to predict the potential for a limb defect in vivo.
If the moral value of a zygote/embryo is in its potential to go on to form a human child, why not extend this moral consideration to every cell capable of inducing an enucleated egg into becoming a zygote/embryo?
One objection is grounded in the assertion that any act of nuclear transfer in which a "reasonably complete human genome" is placed into an enucleated egg directly mimics conception and must be considered the initiation of a human life.
7 mm, the average number of enucleated myomas was 2.
The enucleated tissue and operative time in this study were not different from that of naive HoLEP as previously reported, which indicated the operative efficiency was not inferior to that of conventional HoLEP.
This is indeed a standard alternative method used to introduce the somatic nucleus into an enucleated egg.
All enucleated specimens of retinoblastoma accessioned in the pathology department of Tata Memorial Hospital (Mumbai, India) during the 9 years from January 2000 to September 2008 were studied.
The patient was then returned to the operating room, and the lesion was completely enucleated via a Caldwell-Luc incision.
The Geron researchers are doing this by inserting the genetic material from mature human cells into enucleated human eggs.
16) Then, the enucleated egg cell containing the implanted nucleus is stimulated electrically.
5-cm intratesticular solid lesion with calcified outer walls was enucleated.
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