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an enzyme of the intestinal juice secreted by the duodenal mucosa; it activates the proteolytic enzyme of the pancreatic juice by converting trypsinogen into trypsin.
An intestinal proteolytic glycoenzyme from the duodenal mucosa that converts trypsinogen into trypsin (removes a hexapeptide from trypsinogen).
enterokinase(ĕn′tə-rō-kī′nās′, -nāz′, -kĭn′ās′, -āz′)
An enzyme secreted by the upper intestinal mucosa that catalyzes the conversion of trypsinogen to trypsin.
TMPRSS15A gene on chromosome 21q21 that encodes a serine protease responsible for activating pancreatic proteolytic proenzymes by catalysing the conversion of trypsinogen to trypsin, which in turn activates other proenzymes, including chymotrypsinogen, procarboxypeptidases and proelastases. It is localised at the intestinal brush border.
Defects in TMPRSS15 are a cause of enterokinase deficiency.