enterohepatic recirculation

enterohepatic recirculation

Biliary recycling Therapeutics The cycling of drugs and metabolites after excretion in the biliary system, which are reabsorbed in the intestine. Cf Absorption.
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Other theories include the possibility that carbapenems may limit oral VPA absorption, decrease VPA enterohepatic recirculation, and increase VPA metabolism.
Protein binding changes and drug interactions: What do we know?
This is called enterohepatic recirculation. Binders ensure the products of Phase 1, 2 & 2.5 Detoxification are actually excreted fully from the body through elimination.
Phase 3 Detox
The partner to the gut is the liver and there is an amazing connection called the enterohepatic recirculation, which helps the body process chemicals in the liver and prepare it for non-toxic excretion in the gut.
Are you aging well? How the future of anti-aging medicine and targeted nutritional supplementation will help achieve the optimal aging process
Colchicine is rapidly absorbed in the gastrointestinal (GI) tract and undergoes first-pass hepatic metabolism with enterohepatic recirculation of metabolites prior to excretion via the biliary tract.
The case
The concentration-time profile of EF showed a double peak-shaped curve indicating the possibility of enterohepatic recirculation of EF in geese.
PHARMACOKINETIC STUDY OF ENROFLOXACIN IN TIANFU GEESE
For most antibiotics, the mechanism of interference is at the level of the enterohepatic recirculation of the contraceptives.
Effects of oral contraceptives on the oral cavity
Deconjugation and reabsorption of some bilirubin for enterohepatic recirculation.
Jaundice: an excess of bilirubin
As a result of the prolonged absorption time and enterohepatic recirculation of DDS, methaemoglobinaemia may persist for several days following DDS ingestion.
Acute dapsone overdose: the effects of continuous veno-venous haemofiltration on the elimination of dapsone
This would preclude enterohepatic recirculation in humans, in contrast to rats, in which intestinal [beta]-glucuronidases could break down excreted conjugate and liberate BPA for systemic reabsorption.
Does rapid metabolism ensure negligible risk from bisphenol A?
Most important is the fact that ethinyloestradiol undergoes eventual enterohepatic recirculation. Initially, ethinyloestradiol is subject to first-pass metabolism in the gut mucosa and liver.
Combined oral contraception and broad-spectrum antibiotic use
Serum concentrations of free 8-PN showed rapid drug absorption and secondary peaks suggestive of marked enterohepatic recirculation. Independent of the treatment group, approximately 30% of the dose was recovered in excreta as free compound or conjugates over the 48-h observation period.
Pharmacokinetics and systemic endocrine effects of the phyto-oestrogen 8-prenylnaringenin after single oral doses to postmenopausal women
A high fiber diet reduces circulating estrogens by reducing enterohepatic recirculation of estrogen.
Nutritional Influences on Illness

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