In total, 84.6% (22/26) of patients taking enteric-coated
aspirin suffered both gastric and small intestinal injuries, and gastric and intestinal mucosal injury were significantly associated (Spearman correlation coefficient, 0.662, P < 0.001).
Bhatt's recommendation to clinicians, which predates the publication of this study, is to make sure that patients who are prescribed the immediate-release aspirin get the correct formulation, and not end up with an enteric-coated
, pH-dependent peppermint oil capsules for the treatment of irritable bowel syndrome in children.
In a 2001 study of enteric-coated
garlic tablets, Lawson found that 20 of 24 brands released less than 15% of the allicin potential claimed on the product labels.
medications are formulated to resist gastric-juice action and thereby delay disintegration until reaching the intestine.
To avoid aspirin reactions in the delicate linings of the stomach, many individuals have been taking enteric-coated
aspirin, not realizing that the delayed action in the digestive tract can lead to serious complications.
The FDA approval of YOSPRALA was based on the results from two randomised, double-blind controlled clinical trials that patients were randomly assigned to receive either YOSPRALA 325 mg/40 mg (n=524) or 325 mg of enteric-coated
Tableted products were also tested for their ability to break apart (disintegrate) properly and enteric-coated
products were analyzed to ensure they could withstand stomach acid and then release their contents in the neutral pH environment of the intestines.
Measurements indicating the presence of what has been thought to be aspirin resistance were evident only with enteric-coated
aspirin, not immediate-release aspirin, in a study of 400 healthy adults--a phenomenon the study's authors described as aspirin "pseudoresistance."
According to data from the pivotal phase III studies PN 400-301 and PN400-302, patients taking Vimovo experienced significantly fewer endoscopic gastric ulcers, compared with patients treated with enteric-coated
Both ER minocydine and delayed-release, enteric-coated
doxycycline (Doryx) feature once-a-day dosing that should improve compliance, said Dr.
Study Medication and Dosage: One enteric-coated
, enzyme-rutoside combination (ERC), (Phlogenzym[R], Mucos Pharma, Geretsried, Germany) containing 90 mg bromelain, 48 mg trypsin and 100 mg rutosid t.i.d.