entactin


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en·tac·tin

(en-tak'tin),
A glycoprotein that binds to laminin and type IV collagen in the basal lamina of the renal glomerulus and is a major cell attachment factor; entactin is a sulfated calcium-binding protein.
Synonym(s): nidogen

entactin

a protein that binds LAMININ to type IV COLLAGEN.
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References in periodicals archive ?
It is predominantly composed of laminin with other components including heparin sulfate proteoglycan, entactin, and collagen type IV.
Current Trends in Biomaterial Utilization for Cardiopulmonary System Regeneration
The manufacturer relinquished a vague content for the ECM used in this study which contains entactin, collagen IV, laminin, and heparin sulfate proteoglycan in different concentrations.
Modulation of Inflammatory Reactions by Low-Dose Ionizing Radiation: Cytokine Release of Murine Endothelial Cells Is Dependent on Culture Conditions
Devastation of type IV collagen, laminin, and entactin leads to demotion of anchoring fibers and appearance of bullae [12].
Correlation between IL36[alpha] and IL17 and Activity of the Disease in Selected Autoimmune Blistering Diseases
Broekelmann et al., "Degradation of entactin by matrix metalloproteinases.
Antcin-H Isolated from Antrodia cinnamomea Inhibits Renal Cancer Cell Invasion Partly through Inactivation of FAK-ERK-C/EBP-[beta]/c-Fos-MMP-7 Pathways
Ramadori, "Transforming growth factor-[beta]1 stimulates the synthesis of basement membrane proteins laminin, collagen type IV and entactin in rat liver sinusoidal endothelial cells," Journal of Hepatology, vol.
SECs (Sinusoidal Endothelial Cells), Liver Microenvironment, and Fibrosis
Matrigel is a suitable matrix that includes laminins, collagen IV, entactin, heparan sulfate proteoglycan, as well as various growth factors, which can highly representative of the tumor microenvironment.[sup][18] With the purpose of long-term proliferation of the organoids, multifold factors were added to the overlaid medium.[sup][19] Wnt signals are essential for the proliferation of intestinal epithelium, and the Wnt agonist R-spondin 1 induces crypt hyperplasia in vivo .[sup][20] Signaling by epidermal growth factor (EGF) is associated with intestinal proliferation.[sup][21] Transgenic expression of Noggin induces an expansion of crypt numbers.[sup][22] We added R-spondin-1, EGF, and Noggin to Matrigel to sustain ever-increasing CRC organoids.
Organoid Culture of Isolated Cells from Patient-derived Tissues with Colorectal Cancer
The STBM comprises extracellular matrix (ECM) proteins, such as laminin, collagen IV, perlecan, and entactin (Yazama et al., 1997; Siu and Cheng, 2004).
Effects of extracellular matrix protein-derived signaling on the maintenance of the undifferentiated state of spermatogonial stem cells from porcine neonatal testis
The ECM gel was prepared from Engelbreth-Holm-Swarm (EHS) mouse sarcoma and was composed of laminin as the major component, collagen type IV, heparan sulfate proteoglycan, entactin and other minor components.
Effect of removal of Spermatogonial Stem Cells (SSCs) from in vitro culture on gene expression of niche factors in bovine
Chung, "The basement membrane glycoprotein entactin promotes cell attachment and binds calcium ions," The Journal of Biological Chemistry, vol.
Comparative analysis of glycogene expression in different mouse tissues using RNA-seq data
These enzymes are able to split denatured collagens, fibronectin, lamin, entactin, elastin, etc.
Assessment of activity of matrix metalloproteases 2 and 9 in their interconnection with the level of magnesium ions in the blood of patients with congenital prolapsed of mitral valve
Conditional deletion of Ap-2[alpha] in lens placode derivatives, including the corneal epithelium, results in a decrease in the expression of the cell-cell adhesion molecule E-cadherin, misexpression of laminin, entactin and type IV collagen, and disruption of stromal collagen fibril organization, showing that AP-2[alpha] is required for proper formation of the mouse cornea [179,182].
Ocular surface development and gene expression
(5) MMP-7 displays strong proteolytic activity against a wide range of ECM components including collagen types IV, V, IX, and X, proteoglycans, fibronectin, laminin, gelatin, elastin, and entactin. It also cleaves various non-ECM bioactive molecules such as Fas ligand, pro-tumor necrosis factor [alpha], E-cadherin, [beta]4-integrin, insulin-like growth factor binding protein 3 and insulin-like growth factor binding protein 5, and [alpha]-defensin.
Production and activation of matrix metalloproteinase 7 (matrilysin 1) in the lungs of patients with idiopathic pulmonary fibrosis

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