enoyl

en·o·yl

(ēn'ō-il),
The acyl radical of an unsaturated aliphatic acid.
[-ene + -oyl]
Farlex Partner Medical Dictionary © Farlex 2012

en·o·yl

(ē'nō-il)
The acyl radical of an unsaturated aliphatic acid.
[-ene + -oyl]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Scientists have known for some time that triclosan can halt malaria parasites' growth at the blood stage of the infection by inhibiting the action of an enzyme known as enoyl reductase (ENR), which is involved in production of fatty acids.
Tonge, "Probing mechanisms of resistance to the tuberculosis drug isoniazid: Conformational changes caused by inhibition of InhA, the enoyl reductase from Mycobacterium tuberculosis," Protein Science, vol.
Triclosan's mechanism of antimicrobial action is also concerning as it targets the enzyme enoyl reductase, which is required by most bacteria for fatty acid biosynthesis.
The sequence homology revealed that the gene of interest was ACTTS gene (coding for enoyl reductase) and the test fungal isolates were A.
The binding interaction of the synthesised thiourea via molecular docking interaction in comparison to predicted phenyl thiourea and the targeted compound with enzyme enoyl ACP reductase (FabI) is also thoroughly discussed.
Six different band patterns were identified at the promoter region of inhA gene, which codes for the NADH enoyl ACP reductase enzyme and sensitivity to INH.
The assay has an additional advantage over other line probe assays because the Genotype MTBDRplus assay identifies mutations in the rpoB gene (coding for the [beta]-subunit of the RNA polymerase) for detection of RIF resistance, mutations in the katG gene (coding for the catalase peroxidase) for high-level INH resistance, and mutations in the promoter region of inhA gene (coding for the NADH enoyl ACP reductase) for low-levels INH resistance.
FASN has seven functional domains, namely, acyl carrier protein (ACP), Malonyl/acetyltransferase (MAT), ketoacyl synthase (KS), ketoacyl reductase (KR), dehydrase (DH), enoyl reductase (ER), and thioesterase (TE) [33, 35, 66].
An enzyme involved in [beta]-oxidation of fatty acids (enoyl CoA dehydratase) was also downregulated by taurine deficiency.
If DST indicated isoniazid resistance, DNA sequencing of the catalase-peroxidase G (katG) and enoyl reductase A (inhA) genes (19) was performed at the Public Health Research Institute Tuberculosis Center.
So I was able to start out with a virtual library of compounds that might be active against enoyl reductase [a target for the development of anti-malarial agents].