enkephalins


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Related to enkephalins: encephalitis, Endorphins, somatostatin, substance P

en·keph·a·lins

(en-kef'ă-linz),
Pentapeptide endorphins, found in many parts of the brain, that bind to specific receptor sites, some of which may be pain-related opiate receptors; hypothesized as endogenous neurotransmitters and nonaddicting analgesics. Metenkephalin is Tyr-Gly-Gly-Phe-Met; leuenkephalin has Leu in place of Met; proenkephalin has Pro in place of Met.

enkephalins

See ENDORPHINS.

enkephalins,

n.pl either of the two pentapeptides produced in the body that bind neuroreceptors in brain to alleviate pain.

en·keph·a·lins

(en-kef'ă-linz)
Pentapeptide endorphins, found in many parts of the brain.
References in periodicals archive ?
In other work by George and colleagues (1991), they concluded that a relative lack of enkephalin peptides trans-synaptically, possibly resulting from enhanced enkephalin degradation, might contribute to increased alcohol consumption in C57Bl/6J mice.
Both 1-10 [micro]M of the mu-receptor agonist D-ala2, N-Me-Phe4,Gly-ol5 enkephalin (DAMGO), and 1-10 [micro]M morphine have greater effects on high voltage-activated Ca2+ currents in IB4-negative than in IB4-positive cells (44).
In addition, acupuncture causes the release of enkephalins and endorphins, the body's natural pain relievers.
These gluten fragments have a very similar shape to the body's own endorphins (including enkephalin peptides).
Although there is no evidence for opioid dysfunction per se in CRPS, dysfunction may reside in the descending pain control systems that use endogenous opioids such as enkephalin.
When we feel pain from our physical debility, that pain amplifies our sense of hopelessness; the less hopeful we feel, the fewer endorphins and enkephalins and the more CCK we release.
1, ACE), acting as ectoenzymes on the outer surface of different cells and included in the metabolism of regulatory peptides, like substance P, bradykinin, enkephalins, natriuretic peptides and other vasoactive hormonal peptides (Hooper, 1996).
Eating energy-dense foods with a lot of fat or sugar trigger the release of endorphins and enkephalins, the brain's natural opioids which, in turn, stimulate a squirt of dopamine, generating a feeling of reward.
For instance, several therapies stimulate the production of the body's own analgesics, known as enkephalins and endorphins.
These substances are called endorphins, enkephalins and substance P.
The released chemical substances have been purified and some of them are mainly the natural substances resembling morphine called enkephalins.