engraftment


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engraftment

 [en-graft´ment]
incorporation of grafted tissue into the body of the host.

engraftment

Transplantation The process by which transplanted or transfused cells–eg, in BM–from an allogeneic donor grow and reproduce with a recipient. See Bone marrow transplantation.

Engraftment

The process of transplanted stem cells reproducing new cells.
References in periodicals archive ?
Williams suggested that a new imaging agent can safely show engraftment as early as days after transplant--giving a helpful and hopeful preview to patients and their doctors.
Engraftment and survival following reduced-intensity allogeneic peripheral blood hematopoietic cell transplantation is affected by CD8+ T-cell dose.
Engraftment was achieved with 1.1x[10.sub.3]/[micro]L neutrophils on post-transplant day 12.
In a separate oral presentation, Kevin Goncalves of Magenta highlighted preclinical data demonstrating that the high stem cell dose in MGTA-456 accelerates and improves engraftment of human microglia in transplanted mice.
Engraftment post IUT has also been shown for amniotic fluid-derived cells [48, 49] and hepatocytes [50, 51].
The endpoints of this study were engraftment, aGVHD and cGVHD, infectious complications, non-relapse mortality (NRM), relapse rate, disease-free survival (DFS), and overall survival (OS).
Engraftment of embryos was determined by means of a veterinarian ultrasonic diagnostic apparatus on the 45th day of the sexual cycle and on the 2nd month of pregnancy.
"We are seeing what we believe to be dose-dependent marked increases in both absolute CD4 cell counts as well as the engraftment of CCR5 modified T cells with the increasing doses of Cytoxan," he said at the Conference on Retroviruses and Opportunistic Infections 2014.
PBSC transplantation (PBSCT) has become increasingly common with PBSCs largely replacing bone marrow (BM) as the preferred stem cell source due largely to quicker engraftment kinetics and ease of collection.
Fate Therapeutics discovered that the human cord blood was being handled at temperatures too cold for the prostaglandin to biologically activate the stem cells and improve their engraftment properties.