engraftment

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engraftment

 [en-graft´ment]
incorporation of grafted tissue into the body of the host.

engraftment

Transplantation The process by which transplanted or transfused cells–eg, in BM–from an allogeneic donor grow and reproduce with a recipient. See Bone marrow transplantation.

Engraftment

The process of transplanted stem cells reproducing new cells.
References in periodicals archive ?
The data strongly suggest that AST-OPC1 cells have engrafted in these patients post-implantation and have the potential to prevent lesion cavity formation, possibly reducing long-term spinal cord tissue deterioration after spinal cord injury, according to Edward Wirth, chief medical officer.
The proposed regulations would thus engraft a further loss limitation on section 382 that appears unsupported by the statue and legislative history.
Cord Blood America, Inc., an umbilical cord blood stem cell preservation company based in Las Vegas, NV, announced it will pay a the owner of umbilical cord blood stem cells $50,000 if the stem cells stored with the company are used in a hematopoietic stem cell transplant and the stem cells fail to engraft.
In February 2018, Asterias reported additional results from the SCiStar study that continued to support AST-OPC1's positive safety profile and its potential to durably engraft and help restore upper extremity motor function improvement to individuals with severe cervical spinal cord injuries.
Rafii, who is also an investigator at the Howard Hughes Medical Institute, said that their work suggests that that an infusion of engineered endothelial cells could engraft into injured tissue and acquire the capacity to repair the organ.
"Rather than having to engraft stem cells into a patient, which can be challenging, we might be able to put those chemical signals into a drug that can be used to deliver the therapy much more easily," said Lane.
The annualization rules regrettably engraft on the determination of estimated tax payments an uncertainty comparable to that which exists in determining a taxpayer's annual taxable income--plus a few additional wrinkles.
The company said it will be testing the structures in rodents to see whether or not they will engraft and start functioning like a real liver.
What Shakespeare now does is graft the new, cultural form of reproduction upon the old, biological form: "And, all in war with Time for love of you,/As he takes from you, I engraft you new." Thus, poetry is to living reproduction what living reproduction is to the enduring hardness of the stone and metal out of which we build monuments to defy time's decay.
But introducing targeted edits into these cells has been challenging, and the edits aren't always stable once the cells engraft in the bone marrow.
For the past 10 years peripheral blood has been the norm as a source of matched related and matched unrelated adult stem cells for transplant because, despite the high risk for GVHD, they are easier to harvest from the donor, they can be stimulated to grow in large numbers prior to harvesting, and they engraft, or set up shop, quickly inside the recipient's body.
"We were a bit surprised to find that cells could engraft fairly robustly with a simple nose drop delivery," Goldstein said.