Other rodent studies have determined that (a) chronic morphine use accelerates the progression of LPS-induced sepsis to septic shock ; (b) both chronic morphine and morphine withdrawal lower host immune defense against IM bacteria (reviewed in ); and (c) the opioid antagonist naltrexone (i.e., a prescription drug used in the management of alcohol and opioid dependence) blocks acute endotoxic
shock in mice by inhibiting TNF-[alpha] production .
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shock susceptibility," Journal of Reproductive Immunology, vol.
Glycine Treatment for Hemorrhagic and Endotoxic
Pan et al., "Deferoxamine attenuates lipopolysaccharide-induced inflammatory responses and protects against endotoxic
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Yen, "Protective effect of baicalein against endotoxic
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Also, rats submitted to endotoxic
shock with lipopolysaccharide (LPS) and treated with ghrelin had higher rates of survival compared to controls .
Interactions of the complement system with endotoxic
lipopolysaccharide: Generation of a factor chemotactic for polymorphonuclear leukocytes.
Release of membrane vesicles containing endotoxic
lipopolysaccharide in Escherichia coli O157:H7 clinical isolated.
Parthenolide, an inhibitor of the nuclear factor-kappaB pathway, ameliorates cardiovascular derangement and outcome in endotoxic
shock in rodents.
Structural prerequisites for endotoxic
activity in the Limulus test as compared to cytokine production in mononuclear cells.
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