endothelium-derived hyperpolarizing factor


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endothelium-derived hyperpolarizing factor

Abbreviation: EDHF
A vasodilating substance released by the vascular endothelium.
See: endothelium
See also: factor
References in periodicals archive ?
A study showed that etomidate increases the responsiveness to norepinephrine in an endothelium-dependent way, which is partially independent of the action of nitric oxide (NO), endothelium-derived hyperpolarizing factor (EDHF), cyclooxygenase products, lipooxygenase products, angiotension-II and Endothelin (15).
CYP2C9 is expressed in the endothelium and, via production of endothelium-derived hyperpolarizing factor (EDHF), may cause vasorelaxation as a result of hyperpolarization of vascular smooth muscle cells by activation of [Ca.