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A medicine that lowers blood pressure by opposing the vasoconstricting effects of endothelins.
See also: antagonist
Medical Dictionary, © 2009 Farlex and Partners
endothelin-receptor antagonistAny drug that blocks the receptors for the artery-narrowing hormone ENDOTHELIN-1 and that can thus be used as a treatment for high blood pressure (HYPERTENSION). An example in BOSENTAN.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005