endothelin-receptor antagonist


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endothelin-receptor antagonist

A medicine that lowers blood pressure by opposing the vasoconstricting effects of endothelins.
See also: antagonist
Medical Dictionary, © 2009 Farlex and Partners

endothelin-receptor antagonist

Any drug that blocks the receptors for the artery-narrowing hormone ENDOTHELIN-1 and that can thus be used as a treatment for high blood pressure (HYPERTENSION). An example in BOSENTAN.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
(9) Food and Drug Administration (FDA)--approved therapies are available in all three groups, either for intravenous or subcutaneous infusion or inhalation (prostanoid therapies) or as oral agents (endothelin-receptor antagonists and phosphodiesterase type-5 [PDE-5] inhibitors).

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