EDNRA

(redirected from endothelin receptor type A)

EDNRA

A gene on chromosome 4q31.22 that encodes endothelin-A receptor, a member of the endothelin receptor group of G-protein-coupled receptors, located primarily in the vascular endothelial cells where they play a role in vasoconstriction, vasodilation, bronchoconstriction and cell proliferation.

Molecular pathology
EDNRA polymorphisms have been linked to migraine headache resistance.
Mentioned in ?
References in periodicals archive ?
It is an investigational therapeutic agent that acts as a potent angiotensin receptor blocker, and a selective endothelin receptor antagonist, with in vitro selectivity toward endothelin receptor type A.

Full browser ?