S1PR4(redirected from endothelial differentiation, G protein coupled receptor 6)
S1PR4A gene on chromosome 19p13.3 that encodes an EDG (endothelial differentiation, G protein-coupled) family receptor for sphingosine 1-phosphate, a bioactive lysophospholipid that regulates cell proliferation, apoptosis, motility and neurite retraction. It acts intracellularly as a second messenger and extracellularly as a receptor ligand, and it elicits diverse physiologic effects on most types of cells and tissues.
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