Endorphins


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Related to Endorphins: dopamine, serotonin

en·dor·phins

(en-dōr'finz, en'dōr-finz),
Opioid peptides originally isolated from the brain but now found in many parts of the body; in the nervous system, endorphins bind to the same receptors that bind exogenous opiates. A variety of endorphins (for example, α, β, and γ) that vary not only in their physical and chemical properties but also in physiologic action have been isolated.
See also: enkephalins.
[fr. endogenous morphine]

endorphins

A number of morphine-like peptide substances naturally produced in the body and for which morphine receptors exist in the brain. Many of these active substances have been found, all with the same opioid core of five amino acids. They are neurotransmitters and have a wide range of functions. They help to regulate heart action, general hormone function, the mechanisms of shock from blood loss and the perception of pain, and are probably involved in controlling mood, emotion and motivation. They are thought to be produced under various circumstances in which acute relief of pain or mental distress is required. At least some of the endorphins are produced by the PITUITARY gland as part of the precursor of the ACTH molecule. Endorphins are fragments cleaved from the beta-lipotropin component of proopiomelanocortin (POMC). The term derives from the phrase ‘endogenous morphines’.

Endorphins

Pain-killing substances produced in the human body and released by stress or trauma. Some researchers think that people who mutilate themselves are trying to trigger the release of endorphins.

en·dor·phins

(en-dōr'finz)
Opioid peptides originally isolated from the brain but now found in many parts of the body.
References in periodicals archive ?
Endorphins are believed to bind to opiate receptors in various areas of the brain and thereby raise the pain threshold.
Endorphins are substances produced only by the human brain.
Further evidence that endorphins figure importantly in pain control comes from a new look at some of the oldest and newest pain treatments.
Endorphins are very psychoactive and account for the warm feelings of falling in love, coping with stress, and bringing joy and contentment.
Fields, senior author of the study, the discovery of the precise locations in the brain where endorphins are released provides a possible target for the development of more effective drugs for the treatment of alcohol abuse.
Endorphins are natural compounds in the body that make us feel happier.
Birmingham-based Cadbury said more women than men (53 per cent versus 38 per cent) knew that chocolate releases endorphins. Paul Hebblethwaite, Cadbury global science director, said: "As chocolate melts in the mouth, the texture and aroma hit all of the senses."
It might not just have been the effect of endorphins which made me feel so happy after my day of hard physical gardening.
Find time for some exercise - this releases endorphins that can relieve tiredness and depression.
The gene participates in production of prodynorphin, an opiumlike protein that serves as a building block for chemical messengers in the brain known as endorphins. Studies have implicated endorphins in the anticipation and experience of pain, in the formation of intimate emotional bonds with others, and in learning and memory:
Not only do you feel good when you laugh, your body is releasing endorphins that could possibly help put an illness into remission.