endomyocardial fibrosis


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fibrosis

 [fi-bro´sis]
formation of fibrous tissue; see also fibroid degeneration. adj., adj fibrot´ic.
congenital hepatic fibrosis a developmental disorder of the liver, marked by formation of irregular broad bands of fibrous tissue containing multiple cysts formed by disordered terminal bile ducts, resulting in vascular constriction and portal hypertension.
cystic fibrosis (cystic fibrosis of pancreas) see cystic fibrosis.
diffuse idiopathic interstitial fibrosis (diffuse interstitial pulmonary fibrosis) idiopathic pulmonary fibrosis.
endomyocardial fibrosis an idiopathic type of myocardiopathy that is endemic in various parts of Africa and rarely in other areas, characterized by cardiomegaly, marked thickening of the endocardium with dense white fibrous tissue that may extend to involve the inner myocardium, and by congestive heart failure.
idiopathic pulmonary fibrosis chronic inflammatory progressive fibrosis of the pulmonary alveolar walls, with steadily progressive dyspnea, resulting in death from oxygen lack or right heart failure. Most cases are of unknown origin, although some are thought to result from pneumoconiosis, hypersensitivity pneumonitis, scleroderma, and other diseases.
mediastinal fibrosis development of hard white fibrous tissue in the upper portion of the mediastinum, sometimes obstructing the air passages and large blood vessels; called also fibrosing or fibrous mediastinitis.
periureteral fibrosis retroperitoneal fibrosis.
pleural fibrosis fibrosis of the visceral pleura so that part or all of a lung becomes covered with a plaque or a thick layer of nonexpansible fibrous tissue. The more extensive form is called fibrothorax.
postfibrinous fibrosis that occurring in tissues in which fibrin has been deposited.
proliferative fibrosis that in which the fibrous elements continue to proliferate after the original causative factor has ceased to operate.
pulmonary fibrosis idiopathic pulmonary fibrosis.
retroperitoneal fibrosis deposition of fibrous tissue in the retroperitoneal space, producing vague abdominal discomfort, and often causing blockage of the ureters, with resultant hydronephrosis and impaired renal function, which may result in renal failure. Called also Ormond disease.
fibrosis u´teri a morbid condition characterized by overgrowth of the smooth muscle and increase in the collagenous fibrous tissue of the uterus, producing a thickened, coarse, tough myometrium.

en·do·my·o·car·di·al fi·bro·sis

thickening of the ventricular endocardium by fibrosis, involving the subendocardial myocardium, and sometimes the atrioventricular valves, with mural thrombosis, leading to progressive right and left ventricular failure with mitral and tricuspid insufficiency; occurs in adults and is endemic in parts of Africa.

endomyocardial fibrosis

Etymology: Gk, endon, within + mys, muscle + kardia, heart; L, fibra, fiber + osis, condition
idiopathic myocardiopathy occurring endemically in various parts of Africa and rarely in other areas, characterized by cardiomegaly; marked thickening of the endocardium with dense, white fibrous tissue that frequently extends to involve the inner third or half of the myocardium; and congestive heart failure.

en·do·my·o·car·di·al fi·bro·sis

(en'dō-mī-ō-kahr'dē-ăl fī-brō'sis)
Thickening of the ventricular endocardium by fibrosis, involving the subendocardial myocardium, and sometimes the atrioventricular valves, with mural thrombosis, leading to progressive right and left ventricular failure with mitral and tricuspid insufficiency; occurs in adults and is endemic in parts of Africa.

endomyocardial fibrosis

Replacement of heart muscle by fibrous tissue, leading to severe loss of pumping action and HEART FAILURE. This is commonest in the tropics in malnourished people with heavy worm infestation. There is often EOSINOPHILIA in the heart. Fibrosis of the heart muscle is also a feature of repeated small heart attacks (MYOCARDIAL INFARCTIONS). See also CARDIOMYOPATHY.

Davies,

J.N.P., U.S. pathologist, 1915–.
Davies disease - thickening of the ventricular endocardium by fibrosis leading to progressive right and left ventricular failure with mitral and tricuspid insufficiency. Synonym(s): endomyocardial fibrosis

endomyocardial fibrosis

see restrictive cardiomyopathy.
References in periodicals archive ?
That was the only epidemiologic study ever done on endomyocardial fibrosis, a restrictive cardiomyopathy that primarily affects children from sub-Saharan Africa.
Diagnostic features of endomyocardial fibrosis by cardiac MRI.
Sarcoidosis Subepicardial progressing inwards, basal Amyloidosis Diffuse, subendocardial to epicardial, altered T1 kinetics Anderson-Fabry disease Mid myocardial, basal inferolateral wall, symmetrically hypertrophied myocardium, normal or increased function Myocarditis Subepicardial progressing inwards, inferolateral/lateral/anteroseptal walls, focal wall-motion abnormalities Chronic myocarditis Mid myocardial, linear ARVD RV-free wall-septum, wall-motion abnormalities, fatty replacement Endomyocardial fibrosis Diffuse subendocardial, adherent thrombus Noncompaction Enhancement of noncompacted myocardium Chagas disease Subepicardial, LV apex, inferolateral wall Muscular dystrophies Inferolateral wall
Endomyocardial fibrosis with thrombotic complications and encephalopathy was the working diagnosis.
Thus archaeal cholesterol oxidase, cholesterol aromatase, cholesterol side chain oxidase, cholesterol hydroxylase and beta hydroxyl steroid dehydrogenase activity were detected in high levels in the patient population of endomyocardial fibrosis, alzheimer's disease, multiple sclerosis, non-hodgkin's lymphoma, metabolic syndrome x with cerebrovascular thrombosis and coronary artery disease, schizophrenia, autism, seizure disorder, creutzfeldt jakob disease and acquired immunodeficiency syndrome.
Chronic calcific pancreatitis (CCP), endomyocardial fibrosis (EMF), multinodular goitre (MNG) and mucoid angiopathy along with the root wilt disease of coconut is endemic to Kerala with its radioactive actinide beach sands.