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formation of fibrous tissue; see also fibroid degeneration. adj., adj fibrot´ic.
congenital hepatic fibrosis a developmental disorder of the liver, marked by formation of irregular broad bands of fibrous tissue containing multiple cysts formed by disordered terminal bile ducts, resulting in vascular constriction and portal hypertension.
cystic fibrosis (cystic fibrosis of pancreas) see cystic fibrosis.
diffuse idiopathic interstitial fibrosis (diffuse interstitial pulmonary fibrosis) idiopathic pulmonary fibrosis.
endomyocardial fibrosis an idiopathic type of myocardiopathy that is endemic in various parts of Africa and rarely in other areas, characterized by cardiomegaly, marked thickening of the endocardium with dense white fibrous tissue that may extend to involve the inner myocardium, and by congestive heart failure.
idiopathic pulmonary fibrosis chronic inflammatory progressive fibrosis of the pulmonary alveolar walls, with steadily progressive dyspnea, resulting in death from oxygen lack or right heart failure. Most cases are of unknown origin, although some are thought to result from pneumoconiosis, hypersensitivity pneumonitis, scleroderma, and other diseases.
mediastinal fibrosis development of hard white fibrous tissue in the upper portion of the mediastinum, sometimes obstructing the air passages and large blood vessels; called also fibrosing or fibrous mediastinitis.
periureteral fibrosis retroperitoneal fibrosis.
pleural fibrosis fibrosis of the visceral pleura so that part or all of a lung becomes covered with a plaque or a thick layer of nonexpansible fibrous tissue. The more extensive form is called fibrothorax.
postfibrinous fibrosis that occurring in tissues in which fibrin has been deposited.
proliferative fibrosis that in which the fibrous elements continue to proliferate after the original causative factor has ceased to operate.
pulmonary fibrosis idiopathic pulmonary fibrosis.
retroperitoneal fibrosis deposition of fibrous tissue in the retroperitoneal space, producing vague abdominal discomfort, and often causing blockage of the ureters, with resultant hydronephrosis and impaired renal function, which may result in renal failure. Called also Ormond disease.
fibrosis u´teri a morbid condition characterized by overgrowth of the smooth muscle and increase in the collagenous fibrous tissue of the uterus, producing a thickened, coarse, tough myometrium.
thickening of the ventricular endocardium by fibrosis, involving the subendocardial myocardium, and sometimes the atrioventricular valves, with mural thrombosis, leading to progressive right and left ventricular failure with mitral and tricuspid insufficiency; occurs in adults and is endemic in parts of Africa.
Etymology: Gk, endon, within + mys, muscle + kardia, heart; L, fibra, fiber + osis, condition
idiopathic myocardiopathy occurring endemically in various parts of Africa and rarely in other areas, characterized by cardiomegaly; marked thickening of the endocardium with dense, white fibrous tissue that frequently extends to involve the inner third or half of the myocardium; and congestive heart failure.
en·do·my·o·car·di·al fi·bro·sis(en'dō-mī-ō-kahr'dē-ăl fī-brō'sis)
Thickening of the ventricular endocardium by fibrosis, involving the subendocardial myocardium, and sometimes the atrioventricular valves, with mural thrombosis, leading to progressive right and left ventricular failure with mitral and tricuspid insufficiency; occurs in adults and is endemic in parts of Africa.
endomyocardial fibrosisReplacement of heart muscle by fibrous tissue, leading to severe loss of pumping action and HEART FAILURE. This is commonest in the tropics in malnourished people with heavy worm infestation. There is often EOSINOPHILIA in the heart. Fibrosis of the heart muscle is also a feature of repeated small heart attacks (MYOCARDIAL INFARCTIONS). See also CARDIOMYOPATHY.
Davies,J.N.P., U.S. pathologist, 1915–.
Davies disease - thickening of the ventricular endocardium by fibrosis leading to progressive right and left ventricular failure with mitral and tricuspid insufficiency. Synonym(s): endomyocardial fibrosis
see restrictive cardiomyopathy.