Endomitosis | definition of endomitosis by Medical dictionary
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mitosis taking place without dissolution of the nuclear membrane, and not followed by cytoplasmic division, resulting in doubling of the number of chromosomes within the nucleus. adj., adj endomitot´ic.
The process or state of duplication of the DNA content of the nuclei without accompanying spindle formation or cytokinesis, resulting in a polyploid nucleus.
[endo- + polyploidy]
A process by which chromosomes replicate without the division of the cell nucleus.
en′do·mi·tot′ic (-tŏt′ĭk) adj.
The process or state of duplication of the chromosomes without accompanying spindle formation or cytokinesis, resulting in a polyploid nucleus.
endomitosis the doubling of the chromosome number without subsequent cell division, so producing a POLYPLOID.
References in periodicals archive
Calcium-and integrin-binding protein 1 regulates endomitosis
and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cells.
Photomicrograph slide of kidney cells showing (a) normal metaphase without chromosome B; (b) normals metaphases with chromosome B; (c) chromosome stickiness; (d) endomitosis
; (e) gaps; (f) breaks; (g) chromosome fragments, and (h) pulverization of P.
In megakaryocyte polyploidization, the cell cycle-related protein and cytoskeletal proteins both play important role in MK endomitosis
. It is suggested that G1 phase progression protein cyclin D1 and G1/S checkpoint protein cyclin E1 are both essential for DNA content enlargement and megakaryocyte polyploidy.
(1985) endoreduplication and endomitosis
constitute the major mechanisms of polyploidization in potato cells.