M2 EQUITYBITES-April 1, 2019-Micreos announces EUR30m for development of
endolysin technology
Global Banking News-April 1, 2019-Micreos announces EUR30m for development of
endolysin technology
M2 PHARMA-April 1, 2019-Micreos announces EUR30m for development of
endolysin technology
We evaluated the in vitro activity of the
endolysin HY-133 against UKM4229 using the broth microdilution method in accordance with ISO 20776-1 guidance (https:IIwww.iso.orgIstandardI41630.html), as described elsewhere (31,32).
Purified
endolysin activity against bacterial was first described in 1959 [96].
Foster-Frey, "Lysis of staphylococcal mastitis pathogens by bacteriophage phi11
endolysin," FEMS Microbiology Letters, vol.
Micreos, a Dutch biotech firm which helped fund the review, is developing Staphefekt, a bacteria-killing enzyme, or
endolysin, specific to S.
Assessment of in vivo anti-staphylococcal activity of the LysSA1
endolysin in septic mice model.
It uses a "designer"
endolysin, Staphefekt, which the scientists engineered to latch on to the surface of bacteria cells and tear them apart.
The discovery also indicated that all the phases carried a gene coding a protein called
endolysin, an enzyme that breaks down bacterial cell walls.
Hatfull and his colleagues also found that the 11 viruses they studied carry a gene for the enzyme
endolysin, which can degrade bacterial cell walls.
The bacteriophage produces a protein, an
endolysin, which recognizes C.