M2 EQUITYBITES-April 1, 2019-Micreos announces EUR30m for development of endolysin
Global Banking News-April 1, 2019-Micreos announces EUR30m for development of endolysin
M2 PHARMA-April 1, 2019-Micreos announces EUR30m for development of endolysin
We evaluated the in vitro activity of the endolysin
HY-133 against UKM4229 using the broth microdilution method in accordance with ISO 20776-1 guidance (https:IIwww.iso.orgIstandardI41630.html), as described elsewhere (31,32).
activity against bacterial was first described in 1959 .
Foster-Frey, "Lysis of staphylococcal mastitis pathogens by bacteriophage phi11 endolysin
," FEMS Microbiology Letters, vol.
Micreos, a Dutch biotech firm which helped fund the review, is developing Staphefekt, a bacteria-killing enzyme, or endolysin
, specific to S.
Assessment of in vivo anti-staphylococcal activity of the LysSA1 endolysin
in septic mice model.
It uses a "designer" endolysin
, Staphefekt, which the scientists engineered to latch on to the surface of bacteria cells and tear them apart.
The discovery also indicated that all the phases carried a gene coding a protein called endolysin
, an enzyme that breaks down bacterial cell walls.
Hatfull and his colleagues also found that the 11 viruses they studied carry a gene for the enzyme endolysin
, which can degrade bacterial cell walls.
The bacteriophage produces a protein, an endolysin
, which recognizes C.