Endolymphatic sac surgery was first defined by Portmann in 1927.
 over two randomized controlled studies showed that no significant effect could be achieved using the endolymphatic sac surgery, providing insufficient evidence for the beneficial effect.
To summarize, they are the use of the operating microscope, tympanoplasty and mastoidectomy techniques, stapes surgery, endolymphatic sac surgery
for intractable Meniere's disease, skull base surgery (for example, removal of vestibular schwannomas, vestibular nerve sections), use of intratympanic gentamycin, and cochlear implantation, not to mention the discovery of new diseases.
Endolymphatic sac surgery
: Patients are hospitalised overnight and this surgery relieves the dizziness in about 75 per cent of patients and is maintained in 50-60 per cent of cases.
 found a correlation between reduction of ear fullness and endolymphatic sac surgery
, which has been suggested to have a possible relation between ear fullness and EH.
(22) During endolymphatic sac surgery, Huang used 1 mg/ml for 5 minutes.
In 1999, Yazawa et al published their experience with mitomycin C during endolymphatic sac surgery, and they reported no heating impairment or dizziness among 14 patients who had been followed for more than 6 months.
Recent surveys have indicated that the most common surgical procedure for intractable or progressive Meniere's disease is endolymphatic sac surgery
. This is, of course, a transmastoid operation, and the sac is located in the dura.
We did determine that endolymphatic sac surgery
resulted in a lower incidence of postoperative hearing loss than did either vestibular neurectomy or intratympanic gentamicin (figure 3).
Revision endolymphatic sac surgery
for recurrent Meniere's disease.
Preservation procedures include endolymphatic sac surgery
 According to another study, a deposition of immunoglobulin G was observed in 40% of endolymphatic sac specimens obtained during endolymphatic sac surgery
from patients with Meniere's disease.