endocytosis


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

endocytosis

 [en″do-si-to´sis]
the uptake by a cell of material from the environment by invagination of the plasma membrane; it includes both phagocytosis and pinocytosis.
Endocytosis. Shown are pinocytosis of small fluid droplets (left) and phagocytosis of a large particle (right). From Dorland's, 2000.

en·do·cy·to·sis

(en'dō-sī-tō'sis),
Internalization of substances from the extracellular environment through the formation of vesicles formed from the plasma membrane. There are two forms: (a) fluid phase (pinocytosis), and (b) receptor mediated.
See also: phagocytosis. Compare: exocytosis (2).
[endo- + G. kytos, cell, + -osis, condition]

endocytosis

/en·do·cy·to·sis/ (-si-to´sis) the uptake by a cell of material from the environment by invagination of its plasma membrane; it includes both phagocytosis and pinocytosis.

endocytosis

(ĕn′dō-sī-tō′sĭs)
n.
A process of cellular ingestion by which the plasma membrane folds inward to bring substances into the cell.

en′do·cyt′ic (-sĭt′ĭk), en′do·cy·tot′ic (-sī-tŏt′ĭk) adj.
en′do·cy·tose′ (-tōs′) v.

endocytosis

[en′dōsītō′sis]
Etymology: Gk, endon, within, + kytos, cell
uptake by a cell of material from the environment by invagination of its plasma membrane, which may be either phagocytosis or pinocytosis. Compare exocytosis.
enlarge picture
Endocytosis

en·do·cy·to·sis

(en'dō-sī-tō'sis)
Internalization of substances from the extracellular environment through the formation of vesicles formed from the plasma membrane.
See also: phagocytosis
Compare: exocytosis (2)
[endo- + G. kytos, cell, + -osis, condition]

endocytosis

A method by which a large molecule, such as a protein, can enter a cell. The plasma membrane of the cell is invaginated by the molecule so that an internal vesicle is formed containing the molecule. This then breaks off from the surface membrane and moves into the interior of the cell. Such vesicles are coated with a protein called clathrin.

endocytosis

an active process by which some cells can enclose a smaller body (e.g. a food particle) forming a membrane-bound vesicle. Compare EXOCYTOSIS. See PHAGOCYTOSIS, PINOCYTOSIS.

endocytosis

the uptake by a cell of material from the environment by invagination of the plasma membrane; it includes both phagocytosis and pinocytosis.

receptor mediated endocytosis
uptake of materials bound to specific cell-surface receptors by invagination of the plasma membrane to form a small membrane-bounded vesicle; a mechanism for entry of viruses into cells.
References in periodicals archive ?
Mice lacking renal chloride channel, CLC-5, are a model for Dent's disease, a nephrolithiasis disorder associated with defective receptor-mediated endocytosis.
At the same time, the cells use endocytosis to carefully adjust the quantity of signal molecules on the cell membrane and in the endosomes - endocytosis and signalling pathways thus influence each other.
Thus, by linking parkin to endophilin-A, a protein at the heart of synaptic vesicle endocytosis and ecycling, our findings provide a molecular link between recessive Parkinson's genes and defects in synaptic transmission.
Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-[beta]-arrestin complexes after receptor endocytosis.
Mammalian (HeLa) and Dictyostelium discoideum (AXS) cells were observed to incorporate avidin and DHLA-conjugated CdSe/ZnS QDs via endocytosis (Jaiswal et al.
LDL bound to the cell-surface LDLR is internalized by receptor-mediated endocytosis, discharged from its receptor, and degraded in the lysosomes; subsequently, the receptor is recycled to the cell surface (5).
The researchers were surprised to find that most of the particles in the cellular cytoplasm were not attached to the membrane, as would have been expected if the particles had been encapsulated through endocytosis or phagocytosis.
LRP1 is also up-regulated in many tumors, therefore once in the brain, GRN1005 may gain entry into tumor cells using the same receptor by a process known as endocytosis.
Endocytosis dependent on ubiquitin (Ub) has been mostly involved in the retrieval of cell-surface proteins and their targeting to the lysosome/vacuole for degradation in mammals and yeast.
Targeting the transferrin receptor-mediated endocytosis pathway 82
There are at least four basic mechanisms, most of which can be demonstrated in lungs and involve specific receptor-ligand interactions: a) macropinocytosis, b) clathrin-mediated, actin-based endocytosis, c) caveolae-mediated endo- or transcytosis, and d) clathrin- and caveolae-independent endocytosis (Conner and Schmid 2003).
Thus, there is evidence that, generally, Gc and Gc-25OHD complexes are filtered in the glomerulus and reabsorbed by megalin-mediated endocytosis into the proximal tubular cells, where vitamin D activation takes place.