Use of endocytoscopy for identification of sessile serrated adenoma/polyps and hyperplastic polyps by quantitative image analysis of the luminal areas.
Efficiency of endocytoscopy in differentiating types of serrated polyps.
Sugimoto et al., "Endocytoscopy
can be used to assess histological healing in ulcerative colitis," Endoscopy, vol.
The prospective study, led by Dr Yuichi Mori from Showa University in Yokohama, Japan, involved 250 men and women in whom colorectal polyps had been detected using endocytoscopy
Mori et al., "Classification of nuclear morphology in endocytoscopy
of colorectal neoplasms," Gastrointestinal Endoscopy, vol.
New technologies, such as narrow band imaging (NBI), (7-9) photodynamic diagnosis (PDD), (10-15) optical coherence tomography (OCT), (16-19) confocal endomicroscopy (CLE), (20-22) and endocytoscopy (23) have been used for better in vivo visualization and characterization of bladder cancers, especially CIS.
New high-resolution optical imaging techniques, such as OCT, CLE, and endocytoscopy, (16,18,20-23) are being explored to bring down the high false-positive rates associated with the abovementioned macroscopic techniques.
Endocytoscopy. Endocytoscopy (Olympus, Japan) is based on the optical principle of contact light microscopy, delivering in vivo real-time ultra-magnifying microscopic imaging of the mucosal surface at a magnification up to 1390-fold [48, 49].
Wong Kee Song et al., "Endocytoscopy," Gastrointestinal Endoscopy, vol.
Some optical biopsy techniques have been used to evaluate human lung pathology with in vivo optical coherence tomography, confocal endomicroscopy, and endocytoscopy
. (27-35) Optical coherence tomography, the most mature of those technologies, is an interference-based optical imaging technique, similar, in principle, to ultrasound imaging.
More recently, endocytoscopy
and confocal endomicroscopy provide real-time microscopic images at no less than 100-fold magnification during ongoing endoscopy [15, 16].
Confocal Laser Endomicroscopy and Endocytoscopy
. Confocal laser endomicroscopy (CLE) was developed to enable living cellular and microvascular structures visualized with magnification level up to 1,000-fold and to provide better spatial resolution than conventional fluorescence microscopy .