endocrine disruptor


Also found in: Acronyms, Wikipedia.

endocrine disruptor

A substance which interferes with the synthesis, secretion, transport, binding, action or elimination of natural hormones in the body that are responsible for development, behaviour, fertility and maintenance of homeostasis (normal cell metabolism).

Examples
DDT, polychlorinated biphenyls, bisphenol A, polybrominated diphenyl ethers, phthalates.

endocrine disruptor

(dĭs-rŭp′tĕr)
A chemical that may imitate or block the function of natural hormones if it is absorbed by the body. Many pesticides and plasticizing compounds, e.g., phthalates, are thought to disrupt endocrine pathways, esp. if they are absorbed by pregnant women during embryonic and fetal development.
Mentioned in ?
References in periodicals archive ?
With the knowledge that such tiny amounts of BPA can have such far-reaching implications for humans and wildlife, stricter regulations of this chemical and other endocrine disruptors should be fast on its heels.
In the case of the families studied, researchers surmised that plastic food packaging and restaurant meals were the most likely dietary sources of the endocrine disruptors.
In 2002, the joint International Programme on Chemical Safety (IPCS) of the World Health Organization (WHO), the United Nations Environment Programme (UNEP), and the International Labour Organisation (ILO) published a report titled Global Assessment of the State-of-the-Science of Endocrine Disruptors (http://www.
The EFSA begins by distinguishing between endocrine active substances and endocrine disruptors.
BPA is not the only endocrine disruptor babies are exposed to.
The EDSP flags potential endocrine disruptors with a two-tiered system.
A new mouse study illustrates activation of a specific PPAR isotype with exposure to the endocrine disruptor diethylhexyl phthalate (DEHP) and provides evidence that the potential influence of DEHP exposure on diet-induced obesity may vary between species [EHP 118:234-241; Feige et al.
LTG 3, which involves support of the Endocrine Disruptor Screening and Testing Program of the U.
EPA's Endocrine Disruptor Screening Program (EDSP) screens and tests chemicals to determine potential endocrine effects in humans and wildlife.
But ClientEarth environmental lawyer Alice Bernard said: "Now BPA is finally recognised as an endocrine disruptor, the EU and national governments must act fast to limit the irreversible damage this chemical does to people and the environment.
An example for a compound that is used in topical consumer products and has been identified as a potential endocrine disruptor is the antimicrobial agent triclosan.