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endocrine/en·do·crine/ (en´do-krin, en´do-krīn)
menopauseChange of life, climacteric, 'time of life' Gynecology The cessation of menstrual activity due to failure to form ovarian follicles, which normally occurs age 45–50 Clinical Menstrual irregularity, vasomotor instability, 'hot flashes', irritability or psychosis, ↑ weight, painful breasts, dyspareunia, ↑/↓ libido, atrophy of urogenital epithelium and skin, ASHD, MI, strokes and osteoporosis–which can be lessened by HRT. See Estrogen replacement therapy, Hot flashes, Male menopause, Premature ovarian failure, Premature menopause. Cf Menarche.
hypertensionHigh blood pressure Cardiovascular disease An abnormal ↑ systemic arterial pressure, corresponding to a systolic BP of > 160 mm Hg and/or diastolic BP of 95 mm Hg and graded according to intensity of ↑ diastolic BP; HTN affects ± 60 million in the US Workup Evaluation of HTN requires clinical Hx for Pt, family Hx, 2 BP determinations, funduscopy, ID of bruits in neck & abdominal aorta, evaluation of peripheral edema, peripheral pulses and residual neurologic defects in stroke victims, chest films to determine cardiac size and lab parameters to rule out causes of secondary HTN Risk factors Race–blacks more common, ♂, family history of HTN, obesity, defects of lipid metabolism, DM, sedentary lifestyle, cigarette smoking, electrolyte imbalance–eg, ↑ sodium, phosphorus, ↓ potassium, tin Treatment Diet–eg, sodium restriction, ↓ calories, alcohol and cigarettes–the weight gain accompanying smoking cessation tends to offset the minimal ↓ in BP, calcium supplements, lifestyle manipulation–eg, biofeedback, ↑ exercise; antihypertensives–eg, diuretics–benzothiadiazines, loop diuretics, potassium-sparing diuretics, sympatholytic agents–central and peripheral-acting α-adrenergics, β-adrenergics, mixed α- and β-blockers, direct vasodilators, ACE inhibitors–the preferred agent to use ab initio, dihydropiridine CCBs. See ACCT, ACE inhibitor, Borderline hypertension, Borderline isolated systolic hypertension, Calcium channel blocker, Drug-induced hypertension, Essential hypertension, Exercise hypertension, Familial dyslipemic hypertension, Gestational hypertension, Idiopathic intracranial hypertension, Isolated systolic hypertension, Malignant hypertension, MRC, Obetension, Paradoxic hypertension, Pill hypertension, Pregnancy-induced hypertension, Pseudohypertension, Pulmonary hypertension, Refractory hypertension, Renovascular hypertension, SHEP, STOP-Hypertension, TAIM, TOHP-1, TOMHSTyramine hypertension, White coat hypertension.
endocrinerelated to internal secretions: adj describing (1) glands or organs that produce and secrete hormones directly into the blood stream; (2) tissues not in the form of discrete glands that produce and secrete hormones into local body fluids or into the blood stream; (3) the secretions of such glands or tissues; (4) the whole-body system or function that involves the production, secretion and action of hormones. See also hormones; Table 1.
|Site of production||Name of hormone||Main targets||Involved in regulating:||Secretion controlled by:|
|Hypothalamus||Releasing and inhibiting hormones||Anterior pituitary (via local blood vessels)||Secretion of anterior pituitary hormones||Other brain regions; feedback re regulated hormones and their actions|
|Neurohormones released from posterior pituitary:|
|Oxytocin||Uterus, breasts||Labour and lactation||Afferent information from target organs|
|Antidiuretic hormone (ADH, vasopressin)||Kidneys||Water loss: ECF volume and osmolality||Hypothalamic osmoreceptors|
|Anterior pituitary||(Human) growth hormone (H)GH||Most cells||Growth and metabolism||Hypothalamic releasing and inhibiting hormones via local blood vessels|
|Thyroid-stimulating (TSH)||Thyroid gland||Thyroid secretions|
|Gonadotrophins||Ovary or testis||Germ cell maturation and hormone secretions|
|Adrenocorticotrophic (ACTH)||Adrenal cortex||Cortisol secretion|
|Pineal body||Melatonin||Widespread, including brain, thymus, etc.||Hypothalamus; varying light input from retina|
|Parathyroids||Parathormone||Bone, kidneys, gut||ECF [Ca2+]|
|Medulla||Heart, smooth muscle, glands||Cardiovascular and metabolic adjustments to activity and stress||Sympathetic nervous system|
|Atrial wall||Atrial natriuretic hormone||Kidneys||Blood volume; increases sodium (therefore also water) loss in urine||Stretch of atrial wall by venous pressure|
|Gonads: Testis||Androgens (mainly testosterone)||Genitalia and other tissues||Reproductive function and sex characteristics||Anterior pituitary gonadotrophins|
|Ovary||Uterus, breasts and other tissues||Menstrual cycle, pregnancy, lactation|
|Pancreas||Blood levels, storage and cellular uptake of nutrients, notably glucose, but also proteins and fats||Blood levels of nutrients; autonomic nervous system; other gastrointesinal hormones|
|Stomach||Gastrin||Gastric acid-secreting cells||Gastrointestinal functions: motility, digestive juices and other secretions||Local chemical and mechanical factors in the alimentary tract|
|Small intestine||Several GI functions including bile flow, pancreatic enzyme and exocrine secretions||Ingestion of food, distension of GI tract|
adj refers to either the gland that secretes directly into the systemic circulation or the substance secreted.
Patient discussion about endocrine
Q. Can women think strange when pregnant? Is it due to hormonal imbalance? Please help me; I’m 21 and this is my first pregnancy. I am in the first trimester. Yet I don’t feel morning sickness but feel tired throughout the day. Can women think strange when pregnant? Is it due to hormonal imbalance?
You need not to worry about you're not being nausea during this first trimester. Although morning sickness is a common symptoms of first trimester pregnancy, it doesn't always happened to every pregnant moms. So all you need to do is stay healthy always, by consuming healthy foods, and if you're a working woman, you need to limit your daily works, because first trimester is quite crucial. First trimester is a phase when your fetus is developing its organ, and the attachment to its mother's uterus is becoming strong.
In second trimester, usually there will be less problems, the nausea feeling will often fade away by itself. One other important thing is to get yourself checked to your Ob-GYN doctor (antenatal care), to make sure your pregnancy is okay, and to monitor your baby's development.
In case you're thinking strange, I don't think it is a significant problem. Maybe it's just because this is your very first expe