endocardial fibroelastosis


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fibroelastosis

 [fi″bro-e″las-to´sis]
overgrowth of fibroelastic elements.
endocardial fibroelastosis a condition characterized by left ventricular hypertrophy and conversion of the endocardium into a thick fibroelastic coat, with ventricular capacity sometimes reduced, but often increased, leading to heart failure.

en·do·car·di·al fi·bro·e·las·to·sis

, endomyocardial fibroelastosis [MIM*305300, MIM*226000]
1. a congenital condition characterized by thickening of the left ventricular wall endocardium (chiefly due to fibrous and elastic tissue), thickening and malformation of the cardiac valves, subendocardial changes in the myocardium, and hypertrophy of the heart; chief symptoms are cyanosis, dyspnea, anorexia, and irritability;

endocardial fibroelastosis

A rare congenital heart disease more commonly seen in children under age 2, which is characterised by endocardial fibrosis.

Aetiology
Uncertain; EFE has been associated with infections (especially viral), cardiomyopathy, immune diseases, congenital malformations and lightning.

en·do·car·di·al fi·bro·e·las·to·sis

, endomyocardial fibroelastosis (endō-kahrdē-ăl fībrō-ē-las-tōsis, endō-mī-ō-)
Condition characterized by thickening of the left ventricular wall endocardium (chiefly due to fibrous and elastic tissue), thickening and malformation of the cardiac valves, subendocardial myocardial changes, and cardiac hypertrophy; chief symptoms are cyanosis, dyspnea, anorexia, and irritability.