Children with trisomy 21 were examined and 10 were found to have endocardial cushion defect
and 11 had ventricular septal defect (VSD).
Most common cardiovascular abnormality in our study was VSD (7.9%) and endocardial cushion defect
(7.9%) followed by ASD (4%).
Complex CHD may be present in up to 18% of patients which include mitral valve prolapse, hypoplastic left heart syndrome, endocardial cushion defect
, coarctation of aorta, patent ductus arteriosus, pulmonary hypertension, Tetrology of Fallot, (5) double outlet right ventricle, (6) truncus arteriosus, and total anomalous pulmonary venous return.
This Saturday I counted 29 patients: 6 with Pott's disease, tuberculosis of the spine; 5 with rheumatic heart disease; 5 with cancer; 4 with congenital spine disease; 1 with TB of the hip; 1 with endocardial cushion defect
; 1 with giant plexiform neurofibroma; and 1 with a fist-sized meningocele.
An echocardiogram showed an endocardial cushion defect
, single atrium, right-sided aorta, pulmonary hypertension, tricuspid regurgitation and situs inversus with levocardia.
Jonathan was a 5-month-old twin with Down Syndrome and complete atrio-ventricular canal (also known as endocardial cushion defect
or atrio-ventricular septal defect) who came to the pediatric intensive care unit (PICU) after surgical repair of his heart defect.
Endocardial cushion defect
was found in 8 cases (1.23%), where in other studies by Kasturi et al., Jain KK et al., Bidwai et al., none of the cases of found.
Common Congenital Heart Disease Terminology AS Aortic Stenosis ASD Atrial Septal Defect AVC Atrioventricular Canal Defect (same as ECD) CHD Congenital Heart Disease CHF Congestive Heart Failure DORV Double Outlet Right Ventricle ECD Endocardial Cushion Defect
(same as AVC) HLHS Hypoplastic Left Heart Syndrome PA Pulmonary Atresia PDA Patent Ductus Arteriosus PGE Prostaglandin E PS Pulmonary Stenosis TGA Transposition of the Great Arteries (or great vessels) TOF Tetralogy of Fallot VSD Ventricular Septal Defect Increased Pulmonary Blood Flow
Cardiac defects (50%) (endocardial cushion defect
, hypoplastic left heart syndrome-HLHS, atrial septal defect-ASD, patent ductus arteriosus-PDA, atrioventricular canal defects, total anomalous pulmonary venous connections-TAPVC) (2)
1993) 1.5 ppm 1,100 ppm L-Transposition (left chest) 1 0 Great vessel defect 1 0 Pulmonary valve defect 1 0 Atrial septal defect 4 7 Ventricular septal defects Subaortic 2 1 Muscular 1 4 Endocardial cushion defect
0 1 Aortic valve defect 0 2 No.
Failure of the endocardial cushions to form will produce a classic congenital heart defect, an AV canal defect (also known as an endocardial cushion defect
Diagnosis should also be followed by an evaluation for other congenital abnormalities such as atrial and/or ventricular septal defects, cor triatriatum, coarctation of the aorta, and endocardial cushion defects
[7, 13, 14].