Children with trisomy 21 were examined and 10 were found to have
endocardial cushion defect and 11 had ventricular septal defect (VSD).
An example of multivariate allometry: We studied the morphological significance of the
endocardial cushion tissue and ventricular myocardium during cardiac development.
Early myocardial function affects
endocardial cushion development in zebrafish.
Most common cardiovascular abnormality in our study was VSD (7.9%) and
endocardial cushion defect (7.9%) followed by ASD (4%).
More complex cardiac lesions such as Tetrology of Fallot,
endocardial cushion defects, double outlet right ventricle, and total anomalous pulmonary venous return are observed uncommonly.
2013), and eight noncritical defects (
endocardial cushion; ventricular septum; atrial septum; valves; aorta; pulmonary artery; heterotaxy; other).
Diagnosis should also be followed by an evaluation for other congenital abnormalities such as atrial and/or ventricular septal defects, cor triatriatum, coarctation of the aorta, and
endocardial cushion defects [7, 13, 14].
It is caused by incomplete expression of
endocardial cushion (6).
(3) The syndrome's variable components include: lung hypoplasia (right more commonly affected than left), partial anomalous pulmonary venous drainage (to right atrium, coronary sinus, inferior vena cava (IVC), or hepatic circulation), absent or small pulmonary artery, systemic arterial supply to the lung, cardiac anomalies (atrial septal defect (ASD), ventricular septal defect (VSD), patent ductus arteriosus (PDA), tetralogy of Fallot, coarctation, hypoplastic left heart or
endocardial cushion defects), diaphragmatic hernia, and anomalies of the bony thorax or thoracic soft tissues.
This Saturday I counted 29 patients: 6 with Pott's disease, tuberculosis of the spine; 5 with rheumatic heart disease; 5 with cancer; 4 with congenital spine disease; 1 with TB of the hip; 1 with
endocardial cushion defect; 1 with giant plexiform neurofibroma; and 1 with a fist-sized meningocele.
An echocardiogram showed an
endocardial cushion defect, single atrium, right-sided aorta, pulmonary hypertension, tricuspid regurgitation and situs inversus with levocardia.
Jonathan was a 5-month-old twin with Down Syndrome and complete atrio-ventricular canal (also known as
endocardial cushion defect or atrio-ventricular septal defect) who came to the pediatric intensive care unit (PICU) after surgical repair of his heart defect.