end-stage disease

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end-stage dis·ease

(endstāj di-zēź)
Generalized term for any disorder that is likely to lead to death in a short time.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Worldwide, the incidence of end-stage disease for organs such as the heart, liver and kidney continues to rise in excess of the supply of these organs.
* Perform longitudinal studies from the earliest events through end-stage disease as a result of shortened duration relative to the clinical course in people living with HIV/AIDS (PLWHA) (median survival is less than 1 year with pathogenic strains of SIV); and
Especially, effects of AVELE on malaria induced critical pathologies such as thrombocytopenia/thrombocytosis and the end-stage disease were examined for the first time.
They plugged in lung cancer detection rates and stage at diagnosis using data from the National Lung Cancer Screening Trial, and data on costs of low-dose CT screening and follow-up, confirmatory bronchoscopy and biopsy, as well as stage-specific costs of lung cancer therapy, including the costs associated with end-stage disease.
They found that end-stage disease occurred in 2.4 per cent of First Nations people who had diabetes, compared to less than one per cent in non-Aboriginal people with diabetes.
As much as 95% of cervical cancer patients in Africa are diagnosed at late- or end-stage disease. The delayed diagnosis for these patients is due to the low level of cancer awareness among the population and health workers, culture and constraints on access to specialised care, which is usually nonexistent.
However, it is limited by the selection of cases, as all of our patients had end-stage disease and needed a liver transplant.
The study included 7,664 men and women enrolled in the Prevention of Renal and Vascular End-Stage Disease (PREVEND) study, which is a prospective investigation of albuminuria and renal and cardiovascular disease.
The metaanalysis was prompted by the findings of 2 component studies [Atherosclerosis Risks in Communities (ARIC) and Prevention of Renal and Vascular End-Stage Disease (PREVEND)] that demonstrated associations of decreased eGFR and albuminuria, respectively, with VTE in post hoc analyses.
The signs and symptoms of advanced/metastatic disease include hepatomegaly, lymphadenopathy (including pelvic masses), jaundice, ascites, and cachexia in end-stage disease. (5) Prostatic malignant neuroendocrine cells tend to produce ectopic peptides, with adrenocorticotropic hormone (ACTH) and calcitonin being detected most frequently in the serum.
Transplant is generally reserved for those with end-stage disease that is refractory to medical therapy.
End-stage disease is characterized by a honeycomb glandular appearance.