end-organ

end-organ

 [end or´gan]
one of the larger, encapsulated endings of sensory nerves. Written also end organ.
References in periodicals archive ?
Neurologic end-organ damage due to hypertensive emergencies includes cerebral infarction, subarachnoid haemorrhage and others.
Chattopadhyay says that while the Street remains fixated on a lack of statistically significant benefit in vaso-occlusive crises from a study "that was not powered for such," he defers to the October 2018 FDA workshop directed at preventing end-organ damage by lowering hemolysis as a "marked evolution in the thought process at the agency."
Seven (32%) of the 22 patients had disseminated candidiasis with end-organ dysfunctions; four (18%) died during their hospitalization.
"Fluid accumulation does occur frequently," he said, "and it is likely a very important and relevant part of practice for bedside providers to be mindful on a multiple-times-a-day basis of what is happening with net fluid balance and how that relates to end-organ function, particularly the lungs and the kidneys."
Viral replication in the recipient results in the virus entering the bloodstream, which can progress to end-organ disease.
"Fluid accumulation occurs frequently," he said, "and it is likely a very important and relevant part of practice for bedside providers to be mindful on a multiple-times-a-day basis of what is happening with net fluid balance and how that relates to end-organ function, particularly the lungs and the kidneys."
Systemic corticosteroids are required for disease exacerbation, and sometimes, adding some other form of immunosuppressive treatment is necessary when serious end-organ involvement occurs.
17, 2018 (HealthDay News) -- For patients with advanced heart failure who are listed for transplantation, mortality risk is related to adverse events and end-organ dysfunction that vary over time, according to a study published in the Aug.
By using non-invasive methods, key pathophysiological changes associated with elevated BP, such as end-organ damage, left ventricular hypertrophy, increased arterial stiffness, [10] lower glomerular filtration rates and proteinuria, can be detected in childhood.
Retinal microvascular changes are a sign of end-organ damage.
"Future studies are warranted to determine whether augmented [sympathetic nerve activity] is associated with deleterious end-organ consequences in persons with anxiety and cardiovascular disease or cardiovascular disease risk factors," the researchers concluded.
The commonly known disease state of monoclonal gammopathy of unknown significance (MGUS) differs from MGRS in that the latter contains objective evidence of renal involvement, indicating end-organ damage.