12 (ANI): The Diabetes Care Foundation of India (DCFI), a non-profit organisation, working extensively on facing the challenge of diabetes, organised a free "diabetes/hypertension related end-organ
damage" screening camp for underprivileged high-risk diabetes patients at a government dispensary in New Delhi on Monday.
5 Hydroxyurea therapy has a proven efficacy when started before the onset of end-organ
damage with close laboratory monitoring and dose adherence.
This was assessed using a primary composite endpoint of overall mortality and CMV end-organ
disease throughout the first year following transplant.
The trial includes 515 subjects and the primary endpoint is a composite of overall mortality and cytomegalovirus (CMV) end-organ
disease which will be assessed one year after transplantation.
Pregnant women with preexisting hypertension or with mild gestational hypertension with systolic blood pressure below 160 mm Hg, a diastolic blood pressure below 105 mm Hg, and no sign of end-organ
damage need not take antihypertensive medications, they said.
As drug overdose is a growing epidemic in this state and country, it is important to consider both apparent and less evident effects of end-organ
damage caused by anoxia following overdose.
Accidental or intentional exposure to mycotoxins, such as aflatoxin and T-2 toxin, can lead to acute liver failure, severe end-organ
injury, bleeding, neurologic damage, coma, and death.
This programme is designed to provide a safety net system to prevent these patients from experiencing the complications of sepsis, such as end-organ
failure and septic shock," Dr Fawzy stated.
The long term end-organ
effects add to patient morbidity and mortality.
The most frequent end-organ
complication involves the kidney, a condition termed diabetic nephropathy, which affects 40-50 percent of patients with type 2 diabetes.
In solid organ transplant recipients, CMV infection is an independent risk factor for organ rejection and nearly one-third of patients develop end-organ
disease in the transplanted organ within the first three postoperative months.
It has long been known that people with a diagnosis of alcohol dependence can moderate their drinking, and that such reductions in consumption reduce end-organ
damage and other adverse health consequences.