Significant reductions from baseline were seen in left atrial volume index (LAVI), LV end-diastolic
volume index (LVEDVI), LV end-systolic volume index (LVESDI), and mitral ratio of early transmitral Doppler velocity/early diastolic annular velocity (E/e') with sacubitril-valsartan.
Abnormal flow indices correlate with intrauterine growth retardation and adverse fetal and neonatal outcomes, particularly when absent or reversed end-diastolic
flow is identified.
There is a strong association between reduced end-diastolic
umbilical artery blood flow velocity and increased vascular resistance in the umbilical placental microcirculation.
The left ventricular (LV) and right ventricular (RV) systolic function were evaluated using the strain imaging method, and LV end-diastolic
and end-systolic volumes were measured by RT3DE.
trans-mitral gradient, Percutaneous transvenous mitral Commissurotomy, Mitral Stenosis.
 suggested that LV elevated end-diastolic
pressure (LVEDP) was significantly associated with CAD as well as its extent and severity.
pressure was elevated, indicative of impaired myocardial relaxation and decreased compliance.
The M-mode echocardiography from the parasternal long axis (perpendicular to the long axis of the ventricle at the level of the mitral valve) measured the left ventricular end-diastolic
diameter, left ventricular end-systolic diameter, interventricular septum thickness, and posterior wall thickness.
The end-systolic and end-diastolic
dimensions (ESD, EDD) and end-diastolic
ventricular septal thickness were measured via M-mode.
and end-systolic diameters and systolic and diastolic septum and the posterior wall thickness of the left ventricle were measured using echocardiography in M-mode through the parasternal short-axis view.
Cardiac output is the product of stroke volume and heart rate, and the stroke volume can be obtained by measuring the area and velocity time integral of the LV outflow tract (LVOT), and the value is close to the result obtained by the pulmonary artery catheter., Left systolic function can be assessed by LV ejection fraction, which can be calculated indirectly from the LV fractional shortening by measuring the LV end-systolic diameter and end-diastolic
diameter in patients without regional dysfunction.
There was no difference in LVEF, LV end-diastolic
and end-systolic diameter, LV end-diastolic
and end-systolic volume between the two treatment arms at baseline.