feedback inhibition

feed·back in·hi·bi·tion

inhibition of activity by an end product of the pathway of which that activity is a part; for example, thyroliberin stimulates thyroglobulin production, and thyroglobulin decreases thyrotropin formation.

Synonym(s): end product inhibition, retroinhibition

feedback inhibition

n.

A cellular control mechanism in which an enzyme that catalyzes the production of a particular substance in the cell is inhibited when that substance has accumulated to a certain level, thereby balancing the amount provided with the amount needed.

feed·back in·hi·bi·tion

(fēd'bak in'hi-bish'ŭn)

Inhibition of activity by an end product of the pathway of which that activity is a part.
Synonym(s): feedback mechanism.

feedback inhibition

the inhibition of the synthesis of a molecule by a control mechanism initiated by the increase in concentration of that molecule.

Kiliani,

H., German chemist, 1855-1945.

Kiliani-Fischer reaction - Synonym(s): Kiliani-Fischer synthesis

Kiliani-Fischer synthesis - a synthetic procedure for the extension of the carbon atom chain of aldoses by treatment with cyanide. Synonym(s): feedback inhibition; Kiliani-Fischer reaction